Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26333152 | 0.86 | ALDH1A1 (0.40) | — | |
| SCHEMBL20664158 | 0.81 | LMNA (0.39) | LMNATSHRSMN1; SMN2MAPT | |
| SCHEMBL25807299 | 0.72 | PRMT3 (0.37) | — | |
| SCHEMBL8756236 | 0.69 | LMNA (0.39) | LMNATSHRSMN1; SMN2MAPT | |
| SCHEMBL15080934 | 0.68 | TDP1 (0.32) | LMNATSHR | |
| SCHEMBL17525672 | 0.68 | LMNA (0.38) | LMNATSHRSMN1; SMN2MAPT | |
| SCHEMBL18716653 | 0.68 | TSHR (0.39) | LMNATSHR | |
| SCHEMBL14042865 | 0.67 | — | — | |
| SCHEMBL14819990 | 0.66 | — | — | |
| SCHEMBL17432996 | 0.66 | KMT2A (0.50) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4249480-A1 | DIPHENYLPYRAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Northwest A&F University (CN) | 2023-09-27 | — | — | EP | disclosed |