Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | FGF2 | P09038 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL43959 | 0.81 | TSHR (0.39) | SMN1; SMN2HPGDHTTALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL17595174 | 0.79 | TSHR (0.38) | SMN1; SMN2HPGDHTTALDH1A1MEN1 | |
| SCHEMBL10495316 | 0.78 | SMN1; SMN2 (0.41) | SMN1; SMN2HPGDHTTALDH1A1MAPT | |
| Hydroxyamine SCHEMBL3213770 | 0.78 | TSHR (0.37) | SMN1; SMN2HPGDALDH1A1POLBMEN1 | |
| SCHEMBL24287571 | 0.75 | SMN1; SMN2 (0.46) | SMN1; SMN2HPGDHTTALDH1A1MAPT | |
| SCHEMBL23615406 | 0.73 | SMN1; SMN2 (0.53) | SMN1; SMN2HPGDHTTALDH1A1MAPT | |
| SCHEMBL16847757 | 0.72 | SMN1; SMN2 (0.55) | SMN1; SMN2HPGDHTTALDH1A1MAPT | |
| SCHEMBL21322473 | 0.72 | SMN1; SMN2 (0.55) | SMN1; SMN2HPGDHTTALDH1A1MAPT | |
| SCHEMBL57076 | 0.71 | ALDH1A1 (0.54) | SMN1; SMN2HPGDHTTALDH1A1POLB | |
| SCHEMBL9182492 | 0.70 | L3MBTL1 (0.43) | SMN1; SMN2HPGDHTTALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571529-A2 | FUNCTIONAL, CROSS-LINKED NANOSTRUCTURES FOR TANDEM OPTICAL IMAGING AND THERAPY | Mallinckrodt LLC (US) | 2013-03-27 | — | — | EP | disclosed |
| WO-2011143524-A2 | FUNCTIONAL, CROSS-LINKED NANOSTRUCTURES FOR TANDEM OPTICAL IMAGING AND THERAPY | MALLINCKRODT LLC (US) | 2011-11-17 | — | — | WO | disclosed |