Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL43959 | 0.96 | TSHR (0.39) | TSHRSMN1; SMN2RAB9AALDH1A1ALOX12 | |
| Hydrochloric Acid SCHEMBL17595174 | 0.94 | TSHR (0.38) | TSHRSMN1; SMN2RAB9AALDH1A1ALOX12 | |
| Edetic Acid SCHEMBL7787575 | 0.81 | TDP1 (0.40) | TSHRSMN1; SMN2RAB9ALMNAKDM4E | |
| SCHEMBL2352790 | 0.81 | TSHR (0.31) | TSHRSMN1; SMN2RAB9AALDH1A1MEN1 | |
| SCHEMBL4381249 | 0.79 | TSHR (0.38) | TSHRSMN1; SMN2RAB9AALDH1A1ALOX12 | |
| SCHEMBL2634577 | 0.78 | SMN1; SMN2 (0.40) | TSHRSMN1; SMN2ALDH1A1HPGDGAA | |
| SCHEMBL5088057 | 0.74 | TSHR (0.37) | TSHRSMN1; SMN2RAB9AALDH1A1ALOX12 | |
| SCHEMBL5091798 | 0.73 | TSHR (0.44) | TSHRSMN1; SMN2RAB9AALDH1A1ALOX12 | |
| SCHEMBL14769217 | 0.73 | TSHR (0.52) | TSHRSMN1; SMN2RAB9AALDH1A1ALOX12 | |
| SCHEMBL16438029 | 0.70 | TSHR (0.37) | TSHRSMN1; SMN2RAB9AALDH1A1ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010021989-A1 | MULTIPLEX ASSAY FOR RHEUMATOID ARTHRITIS | BIO-RAD LABORATORIES, INC. (US) | 2010-02-25 | — | — | WO | disclosed |
| US-20100047819-A1 | MULTIPLEX ASSAY FOR RHEUMATOID ARTHRITIS | BIO-RAD LABORATORIES, INC. (US) | 2010-02-25 | — | — | US | disclosed |