Dihydromorphine

Dihydromorphine

SCHEMBL26346

CN1CC[C@]23c4c5ccc(O)c4O[C@H]2[C@@H](O)CC[C@H]3[C@H]1C5

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
OPRD1 P41143 7/20 0.71
OPRK1 P41145 6/20 0.71
OPRM1 P35372 6/20 0.71
MRGPRX2 Q96LB1 2/20 0.64
SLC22A1 O15245 1/20 0.64
ADRA2A P08913 1/20 0.64
ARRB1 P49407 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dihydromorphine SCHEMBL12402795 1.00 OPRD1 (0.71) OPRD1OPRK1OPRM1MRGPRX2SLC22A1
Dihydromorphine SCHEMBL2696539 1.00 OPRD1 (0.71) OPRD1OPRK1OPRM1MRGPRX2SLC22A1
Dihydromorphine SCHEMBL29394226 1.00 OPRD1 (0.71) OPRD1OPRK1OPRM1MRGPRX2SLC22A1
Dihydromorphine SCHEMBL19107002 1.00 OPRD1 (0.71) OPRD1OPRK1OPRM1MRGPRX2SLC22A1
Dihydromorphine SCHEMBL13348852 1.00 OPRD1 (0.71) OPRD1OPRK1OPRM1MRGPRX2SLC22A1
Dihydromorphine SCHEMBL19645038 1.00 OPRD1 (0.71) OPRD1OPRK1OPRM1MRGPRX2SLC22A1
Dihydromorphine SCHEMBL13380388 1.00 OPRD1 (0.71) OPRD1OPRK1OPRM1MRGPRX2SLC22A1
Dihydromorphine SCHEMBL19615483 1.00 OPRD1 (0.71) OPRD1OPRK1OPRM1MRGPRX2SLC22A1
Dihydromorphine SCHEMBL17025853 1.00 OPRD1 (0.71) OPRD1OPRK1OPRM1MRGPRX2SLC22A1
Dihydromorphine SCHEMBL15449768 1.00 OPRD1 (0.71) OPRD1OPRK1OPRM1MRGPRX2SLC22A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 11748 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260103736-A1 Methods Of Improving Production Of Morphinan Alkaloids And Derivatives ANTHEIA INC (US) 2026-04-16 US claimed
EP-4724049-A1 MODIFIED RELEASE FILL COMPOSITIONS FOR DOSAGE FORMS AND METHODS OF PREPARATION AND USE THEREOF Catalent Ontario Limited (CA) 2026-04-15 EP claimed
US-20250388939-A1 RECOMBINANT HOST CELLS WITH IMPROVED PRODUCTION OF L-DOPA, DOPAMINE, S-NOROCLAURINE OR DERIVATIVES THEREOF RIVER STONE BIOTECH APS (DK) 2025-12-25 US claimed
US-20250319074-A1 TREATMENT AND MANAGEMENT OF AUGMENTATION IN RESTLESS LEGS SYNDROME UNIV EAST CAROLINA (US) 2025-10-16 US claimed
US-20250283129-A1 PROCESS SUN PHARMACEUTICAL INDUSTRIES AUSTRALIA PTY LIMITED (AU) 2025-09-11 US claimed
EP-4604968-A1 ENHANCED NAD+ COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME Bionadrx Holdings, Inc. (US) 2025-08-27 EP claimed
US-20250255781-A1 PROCESSES FOR PREPARATION OF 3-D PRINTED PHARMACEUTICAL PRODUCTS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-08-14 US claimed
US-12383743-B2 Treatment of addiction and dependency TACA JR ARTURO C (US) 2025-08-12 US claimed
US-20250248938-A1 MEDICAMENT DELIVERY FORMULATIONS, DEVICES AND METHODS HONEYWELL INTERNATIONAL INC. (US) 2025-08-07 US claimed
EP-4594342-A2 METHODS OF IMPROVING PRODUCTION OF MORPHINAN ALKALOIDS AND DERIVATIVES Antheia, Inc. (US) 2025-08-06 EP claimed
EP-0548448-A1 Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer Euro-Celtique S.A. (LU) 1993-06-30 EP claimed
US-4940586-A Skin permeation enhancer compositions using sucrose esters ALZA CORPORATION (US) 1990-07-10 US claimed
US-4806341-A BACKING LAYER, POLYMER MATRIX DISC WITH DRUG MICRODISPERSED THEREIN RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 1989-02-21 US claimed
EP-0046270-B1 NOVEL DERIVATIVES OF BIO-AFFECTING PHENOLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITION CONTAINING THEM INTERx RESEARCH CORPORATION (US) 1986-05-21 EP claimed
US-4464378-A Method of administering narcotic antagonists and analgesics and novel dosage forms containing same UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 1984-08-07 US claimed
EP-0077393-A1 NOVEL METHOD OF ADMINISTERING NARCOTIC ANTAGONISTS AND ANALGESICS AND NOVEL DOSAGE FORMS CONTAINING SAME The University of Kentucky Research Foundation (US) 1983-04-27 EP claimed
WO-1982003768-A1 NOVEL METHOD OF ADMINISTERING NARCOTIC ANTAGONISTS AND ANALGESICS AND NOVEL DOSAGE FORMS CONTAINING SAME UNIV KENTUCKY (US) 1982-11-11 WO claimed
EP-0046270-A1 Novel derivatives of bio-affecting phenolic compounds and pharmaceutical composition containing them INTERx RESEARCH CORPORATION (US) 1982-02-24 EP claimed
US-4126684-A 4-AMINO-3-P-HALOPHENYLBUTYRIC ACIDS AND THEIR DERIVATIVES USED IN THE CONTROL OF NARCOTIC ABUSE CIBA-GEIGY CORPORATION (US) 1978-11-21 US claimed
US-4064228-A Antigens and immunoassays for morphine and related 3-oxybenzomorphan compounds BIOLOGICAL DEVELOPMENTS, INC. (US) 1977-12-20 US claimed