Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 5/20 | 0.62 |
| ▸ | MAP2 | P11137 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | CLK1 | P49759 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | KDM5C | P41229 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | CHUK | O15111 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3242090 | 0.77 | KDM5A (1.00) | KDM5AKDM4EPARP1BRAFKDM5C | |
| SCHEMBL30064094 | 0.77 | KDM5A (1.00) | KDM5AKDM4EPARP1BRAFKDM5C | |
| SCHEMBL31343793 | 0.77 | KDM4E (0.64) | KDM4EALDH1A1HPGD | |
| SCHEMBL14829872 | 0.77 | KDM4E (0.64) | KDM4EALDH1A1HPGD | |
| SCHEMBL4357845 | 0.76 | ALDH1A1 (0.59) | MAP2KDM4EHTTSIRT3TDP1 | |
| SCHEMBL30474111 | 0.75 | KDM5A (0.67) | KDM5AKDM4EPARP1KDM5BCHUK | |
| SCHEMBL19984551 | 0.75 | KDM5A (0.67) | KDM5AKDM4EPARP1KDM5BCHUK | |
| SCHEMBL31546652 | 0.74 | CHUK (0.52) | KDM5AMAP2KDM4ECLK1CDK5 | |
| SCHEMBL4756721 | 0.73 | KDM5A (0.65) | KDM5AKDM4EPARP1DYRK1ABRAF | |
| SCHEMBL246359 | 0.73 | KDM5A (0.65) | KDM5AKDM4EPARP1BRAFKDM5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4249480-A1 | DIPHENYLPYRAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Northwest A&F University (CN) | 2023-09-27 | — | — | EP | disclosed |