Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHUK | O15111 | 7/20 | 0.52 |
| ▸ | BRAF | P15056 | 2/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | MAP2 | P11137 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | TOP1 | P11387 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31546608 | 0.77 | PARP1 (0.56) | CHUKBRAFKIF11MAP2KDM4E | |
| SCHEMBL31546614 | 0.75 | ROCK2 (0.70) | KDM4EALDH1A1ROCK2 | |
| SCHEMBL26347775 | 0.74 | KDM5A (0.62) | CHUKBRAFMAP2KDM4EGABRP | |
| SCHEMBL31546654 | 0.72 | ROCK2 (0.58) | CHUKROCK2CDK5DYRK1A | |
| SCHEMBL1797888 | 0.72 | CHUK (0.59) | CHUKBRAFKIF11KDM4EGABRP | |
| SCHEMBL9149047 | 0.71 | PIM1 (0.50) | CHUKMAP2KDM4EGABRPGABRD | |
| SCHEMBL5802216 | 0.71 | CHUK (0.66) | CHUKMAP2IKBKBPIM1 | |
| SCHEMBL30322777 | 0.71 | CHUK (0.78) | CHUKBRAFKIF11KDM4EGABRP | |
| SCHEMBL12396541 | 0.71 | CHUK (0.78) | CHUKBRAFKIF11KDM4EGABRP | |
| SCHEMBL1802006 | 0.71 | CHUK (0.77) | CHUKBRAFKIF11KDM4EGABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119899184-A | Beta-carboline compound, preparation method thereof and application thereof in resisting Alzheimer disease | 中国人民解放军北部战区总医院 | 2025-04-29 | — | — | CN | disclosed |