Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 2/20 | 0.43 |
| ▸ | MMP3 | P08254 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25254415 | 0.77 | ALDH1A1 (0.53) | ALDH1A1MMP1MMP3MMP2MMP13 | |
| SCHEMBL20401085 | 0.76 | ALDH1A1 (0.76) | ALDH1A1KMT2AMMP1MMP2MMP13 | |
| SCHEMBL25249529 | 0.73 | STS (0.49) | ALDH1A1MMP1MMP3MMP2MMP13 | |
| SCHEMBL17785708 | 0.73 | ALDH1A1 (0.71) | ALDH1A1KMT2AMMP1MMP2MMP13 | |
| SCHEMBL26695878 | 0.72 | ALDH1A1 (0.73) | ALDH1A1KMT2AMMP1MMP2MMP13 | |
| SCHEMBL23877964 | 0.71 | ALDH1A1 (0.67) | ALDH1A1KMT2AMMP1MMP2MMP13 | |
| SCHEMBL29542906 | 0.71 | ALDH1A1 (0.46) | ALDH1A1KMT2AMMP1MMP3MMP2 | |
| SCHEMBL22050819 | 0.69 | STS (0.62) | ALDH1A1MMP1MMP3MMP2MMP13 | |
| SCHEMBL31693773 | 0.69 | ALDH1A1 (0.59) | ALDH1A1KMT2AKDM4EMAPTF2 | |
| SCHEMBL26103168 | 0.68 | ALDH1A1 (0.65) | ALDH1A1KMT2AMMP1MMP3MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4413008-A1 | RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2024-08-14 | — | — | EP | disclosed |
| US-20230303591-A1 | RAS INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT | 2023-09-28 | — | — | US | disclosed |
| WO-2023060253-A1 | RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2023-04-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303591-A1 | RAS INHIBITORS | KRAS, NRAS, HRAS | ALDH1A1 4520/4885KMT2A 3443/4885MMP1 4645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.