Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 9/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12355650 | 0.93 | TSHR (0.63) | EPHX1TSHRALDH1A1RECQLACHE | |
| SCHEMBL7252127 | 0.88 | EPHX1 (0.77) | EPHX1TSHRACHE | |
| SCHEMBL7788927 | 0.85 | EPHX1 (0.82) | EPHX1ALDH1A1ACHE | |
| SCHEMBL7788937 | 0.85 | EPHX1 (0.82) | EPHX1ALDH1A1ACHE | |
| SCHEMBL14252129 | 0.85 | EPHX1 (0.82) | EPHX1ALDH1A1ACHE | |
| SCHEMBL7788569 | 0.85 | EPHX1 (0.82) | EPHX1ALDH1A1ACHE | |
| SCHEMBL717081 | 0.85 | EPHX1 (0.82) | EPHX1ALDH1A1ACHE | |
| SCHEMBL24990587 | 0.84 | ACHE (0.56) | EPHX1TSHRALDH1A1ACHECA12 | |
| SCHEMBL791894 | 0.83 | — | — | |
| SCHEMBL14433357 | 0.83 | EPHX1 (0.70) | EPHX1TSHRACHEGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11773055-B2 | Chemical derivatives and methods for synthesizing and compounding chemical derivatives related to capsaicin palmitate and capsaicin prodrugs | CHORDA PHARMA, INC. (US) | 2023-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11773055-B2 | Chemical derivatives and methods for synthesizing and compounding chemical derivatives related to capsaicin palmitate and capsaicin prodrugs | HCAR2, HCAR3, TRPV1 | EPHX1 716/4885TSHR 4756/4885ALDH1A1 1114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.