Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL743658 | 0.85 | HDAC8 (0.47) | HDAC6HDAC8HDAC2 | |
| SCHEMBL753676 | 0.78 | ALDH1A1 (0.43) | KDM4ECA12CA1ALOX15CA9 | |
| SCHEMBL4064595 | 0.78 | CYP2A6 (0.42) | — | |
| SCHEMBL7988618 | 0.77 | — | — | |
| SCHEMBL1100872 | 0.77 | CA1 (0.48) | KDM4ECA12CA1ALOX15CA9 | |
| SCHEMBL195987 | 0.76 | PARP1 (0.48) | KDM4ECA1HSD17B10 | |
| SCHEMBL745428 | 0.73 | ALDH1A1 (0.41) | — | |
| SCHEMBL1636144 | 0.73 | ATM (0.42) | KDM4E | |
| SCHEMBL3894955 | 0.72 | L3MBTL1 (0.55) | KDM4EHSD17B10 | |
| SCHEMBL4954905 | 0.70 | ALDH1A1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3245273-A1 | BENZOTHIENOTHIOPHENE ISOINDIGO POLYMERS | BASF SE (DE) | 2017-11-22 | — | — | EP | disclosed |
| WO-2016113403-A1 | BENZOTHIENOTHIOPHENE ISOINDIGO POLYMERS | BASF SE (DE) | 2016-07-21 | — | — | WO | disclosed |
| EP-2569340-A1 | POLYPROPYLENE COMPOSITION SUITABLE FOR EXTRUSION COATING | Borealis AG (AT) | 2013-03-20 | — | — | EP | disclosed |
| WO-2012150019-A1 | POLYPROPYLENE FOR FOAM AND POLYPROPYLENE FOAM | BOREALIS AG (AT) | 2012-11-08 | — | — | WO | disclosed |
| WO-2011141070-A1 | POLYPROPYLENE COMPOSITION SUITABLE FOR EXTRUSION COATING | BOREALIS AG (AT) | 2011-11-17 | — | — | WO | disclosed |