SCHEMBL26359373

SCHEMBL26359373

CC(C)(O)Cc1ccc(C(=O)Oc2ccc(S(=O)(=O)O)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PRSS1 P07477 7/20 0.46
▸ ACR P10323 5/20 0.46
▸ MAPT P10636 3/20 0.44
▸ SMN1; SMN2 Q16637 1/20 0.44
▸ KLK1 P06870 2/20 0.44
▸ KDM4E B2RXH2 1/20 0.41
▸ LMNA P02545 1/20 0.41
▸ HSP90AA1 P07900 1/20 0.41
▸ RECQL P46063 1/20 0.41
▸ TDP1 Q9NUW8 1/20 0.41
▸ L3MBTL1 Q9Y468 1/20 0.41
▸ PLG P00747 1/20 0.41
▸ ELANE P08246 2/20 0.40
▸ F2 P00734 1/20 0.39
▸ PRSS2 P07478 1/20 0.39
▸ PRSS3 P35030 1/20 0.39
▸ PKM P14618 1/20 0.39
▸ KMT2A Q03164 1/20 0.39
▸ NR1H4 Q96RI1 1/20 0.39
▸ PTPRB P23467 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26359570 0.87 PRSS1 (0.45) PRSS1ACRMAPTSMN1; SMN2KLK1
SCHEMBL20706308 0.81 MAPT (0.62) MAPTSMN1; SMN2KDM4EHSP90AA1TDP1
SCHEMBL29993865 0.81 MAPT (0.51) PRSS1ACRMAPTSMN1; SMN2KLK1
SCHEMBL9573024 0.81 PRSS1 (0.48) PRSS1ACRMAPTSMN1; SMN2KLK1
SCHEMBL15279259 0.81 MAPT (0.51) PRSS1ACRMAPTSMN1; SMN2KLK1
SCHEMBL9726291 0.78 ACR (0.61) PRSS1ACRMAPTSMN1; SMN2KDM4E
SCHEMBL9726260 0.77 STS (0.57) PRSS1ACRMAPTSMN1; SMN2LMNA
SCHEMBL7183003 0.77 ACR (0.65) PRSS1ACRMAPTSMN1; SMN2KDM4E
SCHEMBL14567085 0.76 LMNA (0.59) PRSS1ACRMAPTSMN1; SMN2LMNA
SCHEMBL26357336 0.76 MAPT (0.44) PRSS1ACRMAPTSMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11773059-B2 Onium salt, chemically amplified negative resist composition, and pattern forming process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-10-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11773059-B2 Onium salt, chemically amplified negative resist composition, and pattern forming process LBR, IDUA, ADORA1 PRSS1 3997/4885ACR 3000/4885MAPT 1883/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback