Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 4/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 3/20 | 0.40 |
| ▸ | UBA2 | Q9UBT2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 3/20 | 0.40 |
| ▸ | APAF1 | O14727 | 3/20 | 0.40 |
| ▸ | CASP3 | P42574 | 3/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | UBE2I | P63279 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16740896 | 0.75 | ALDH1A1 (1.00) | ALDH1A1KDM4EGAACYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL16740892 | 0.73 | ALDH1A1 (0.96) | ALDH1A1KDM4EGAACYP1A2CYP2C19 | |
| SCHEMBL11577886 | 0.71 | ALDH1A1 (0.60) | ALDH1A1KDM4EGAACYP1A2CYP2C19 | |
| SCHEMBL28820480 | 0.68 | ALDH1A1 (0.51) | ALDH1A1KDM4ECYP1A2CYP2C19TNKS2 | |
| SCHEMBL18156327 | 0.67 | TNKS (0.60) | ALDH1A1KDM4EGAATNKS2CDC25B | |
| SCHEMBL9754369 | 0.66 | NOTUM (0.48) | ALDH1A1KDM4EGAAHPGDAPAF1 | |
| SCHEMBL1264748 | 0.65 | ALDH1A1 (0.44) | ALDH1A1KDM4EGAACYP1A2CYP2C19 | |
| SCHEMBL29488099 | 0.63 | KDM4E (1.00) | ALDH1A1KDM4EGAACYP1A2TNKS2 | |
| SCHEMBL824574 | 0.63 | KDM4E (1.00) | ALDH1A1KDM4EGAACYP1A2TNKS2 | |
| SCHEMBL16194439 | 0.61 | ALDH1A1 (0.53) | ALDH1A1KDM4ECYP1A2CYP2C19HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023173016-A1 | KRAS INHIBITORS FOR TREATING DISEASE | BLOSSOMHILL THERAPEUTICS, INC. (US) | 2023-09-14 | — | — | WO | disclosed |
| WO-2023173014-A1 | KRAS INHIBITORS AND THEIR USE | BLOSSOMHILL THERAPEUTICS, INC. (US) | 2023-09-14 | — | — | WO | disclosed |