Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | ERN1 | O75460 | 4/20 | 0.49 |
| ▸ | PRKDC | P78527 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30178662 | 0.90 | ALDH1A1 (0.63) | ALDH1A1ERN1PRKDCKDM4ETSHR | |
| SCHEMBL11173 | 0.90 | ALDH1A1 (0.63) | ALDH1A1ERN1PRKDCKDM4ETSHR | |
| SCHEMBL2636326 | 0.82 | ALDH1A1 (0.58) | ALDH1A1KDM4ETSHRTDP1L3MBTL1 | |
| SCHEMBL5566174 | 0.82 | ALDH1A1 (0.80) | ALDH1A1ERN1KDM4ETSHRTDP1 | |
| SCHEMBL23124622 | 0.78 | ERN1 (0.43) | ALDH1A1ERN1PRKDCL3MBTL1POLB | |
| SCHEMBL2174504 | 0.77 | PRKDC (0.79) | ALDH1A1ERN1PRKDCKDM4ETSHR | |
| SCHEMBL6093571 | 0.76 | ERN1 (0.46) | ALDH1A1ERN1PRKDCKDM4ETSHR | |
| 2-Methoxybenzaldehyde SCHEMBL5070004 | 0.76 | ALDH1A1 (0.54) | ALDH1A1ERN1KDM4ETDP1LMNA | |
| SCHEMBL153974 | 0.75 | ERN1 (0.58) | ALDH1A1ERN1PRKDCKDM4ETSHR | |
| SCHEMBL29890082 | 0.75 | ERN1 (0.58) | ALDH1A1ERN1PRKDCKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2437792-B1 | IMAGING OF MYELIN BASIC PROTEIN | GEN ELECTRIC (US) | 2015-10-21 | — | — | EP | disclosed |
| US-8617515-B2 | Imaging of myelin basic protein | GENERAL ELECTRIC COMPANY (US) | 2013-12-31 | — | — | US | disclosed |
| EP-2437792-A2 | IMAGING OF MYELIN BASIC PROTEIN | General Electric Company (US) | 2012-04-11 | — | — | EP | disclosed |
| WO-2010141704-A2 | IMAGING OF MYELIN BASIC PROTEIN | GENERAL ELECTRIC COMPANY (US) | 2010-12-09 | — | — | WO | disclosed |
| US-20100310457-A1 | IMAGING OF MYELIN BASIC PROTEIN | GENERAL ELECTRIC COMPANY (US) | 2010-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100310457-A1 | IMAGING OF MYELIN BASIC PROTEIN | MAG, PMP22, MYT1 | ALDH1A1 4822/4885ERN1 2631/4885PRKDC 1936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.