Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.80 |
| ▸ | CYP1A2 | P05177 | 10/20 | 0.58 |
| ▸ | CYP1A1 | P04798 | 9/20 | 0.58 |
| ▸ | CYP1B1 | Q16678 | 9/20 | 0.58 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.53 |
| ▸ | TYR | P14679 | 1/20 | 0.53 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.53 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.49 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL96291 | 0.89 | ALDH1A1 (1.00) | ALDH1A1CYP1A2CYP1A1CYP1B1TRIM24 | |
| Hydrochloric Acid SCHEMBL9456784 | 0.88 | ALDH1A1 (0.96) | ALDH1A1CYP1A2CYP1A1CYP1B1TRIM24 | |
| Formaldehyde SCHEMBL28854145 | 0.86 | ALDH1A1 (0.92) | ALDH1A1CYP1A2CYP1A1CYP1B1TRIM24 | |
| Ethylene SCHEMBL4914414 | 0.86 | ALDH1A1 (0.92) | ALDH1A1CYP1A2CYP1A1CYP1B1TRIM24 | |
| SCHEMBL3924348 | 0.84 | ALDH1A1 (0.71) | ALDH1A1CYP1A2CYP1A1CYP1B1TRIM24 | |
| SCHEMBL8356166 | 0.84 | ALDH1A1 (0.75) | ALDH1A1CYP1A2CYP1A1CYP1B1TRIM24 | |
| SCHEMBL2636326 | 0.83 | ALDH1A1 (0.58) | ALDH1A1TRIM24TRIM33MAPTL3MBTL1 | |
| SCHEMBL3376912 | 0.82 | ALDH1A1 (0.58) | ALDH1A1CYP1A2CYP1A1CYP1B1TRIM24 | |
| SCHEMBL2636617 | 0.82 | ALDH1A1 (0.53) | ALDH1A1CYP1A2TRIM24TYRTRIM33 | |
| SCHEMBL3633730 | 0.81 | ALDH1A1 (0.71) | ALDH1A1CYP1A2CYP1A1CYP1B1TRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1529777-B1 | Process and oxazolidine intermediate for the synthesis of taxanes | INDENA SPA (IT) | 2007-01-03 | — | — | EP | claimed |
| US-7053222-B2 | Semi-synthetic process for the preparation of N-debenzoylpaclitaxel | INDENA S.P.A. (IT) | 2006-05-30 | — | — | US | claimed |
| EP-1495011-B1 | A SEMI-SYNTHETIC PROCESS FOR THE PREPARATION OF N DEBENZOYLPACLITAXEL | INDENA SPA (IT) | 2005-12-28 | — | — | EP | claimed |
| US-20050049297-A1 | Semi-synthetic process for the preparation of N-debenzoylpaclitaxel | INDENA S. P. A. (IT) | 2005-03-03 | — | — | US | claimed |
| EP-1495011-A1 | A SEMI-SYNTHETIC PROCESS FOR THE PREPARATION OF N DEBENZOYLPACLITAXEL | INDENA S.p.A. (IT) | 2005-01-12 | — | — | EP | claimed |
| WO-2003087077-A1 | A SEMI-SYNTHETIC PROCESS FOR THE PREPARATION OF N DEBENZOYLPACLITAXEL | INDENA S.P.A. (IT) | 2003-10-23 | — | — | WO | claimed |
| US-7053222-B2 | Semi-synthetic process for the preparation of N-debenzoylpaclitaxel | INDENA S.P.A. (IT) | 2006-05-30 | — | — | US | disclosed |
| EP-1495011-B1 | A SEMI-SYNTHETIC PROCESS FOR THE PREPARATION OF N DEBENZOYLPACLITAXEL | INDENA SPA (IT) | 2005-12-28 | — | — | EP | disclosed |
| US-20050049297-A1 | Semi-synthetic process for the preparation of N-debenzoylpaclitaxel | INDENA S. P. A. (IT) | 2005-03-03 | — | — | US | disclosed |
| EP-1495011-A1 | A SEMI-SYNTHETIC PROCESS FOR THE PREPARATION OF N DEBENZOYLPACLITAXEL | INDENA S.p.A. (IT) | 2005-01-12 | — | — | EP | disclosed |
| WO-2003087077-A1 | A SEMI-SYNTHETIC PROCESS FOR THE PREPARATION OF N DEBENZOYLPACLITAXEL | INDENA S.P.A. (IT) | 2003-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050049297-A1 | Semi-synthetic process for the preparation of N-debenzoylpaclitaxel | UGT2B7, UGT2B17, CYP3A7 | ALDH1A1 824/4885CYP1A2 35/4885CYP1A1 46/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.