SCHEMBL26367018

SCHEMBL26367018

c1ccc2c(c1)oc1c(-c3ccc(Nc4ccc5sc6ccccc6c5c4)cc3)cccc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.48
PTGIR P43119 1/20 0.41
MAPT P10636 1/20 0.38
GGPS1 O95749 1/20 0.37
PRKDC P78527 6/20 0.37
PTGES2 Q9H7Z7 1/20 0.37
CDK2 P24941 1/20 0.35
HDAC8 Q9BY41 1/20 0.34
ESR2 Q92731 2/20 0.33
PIK3CD O00329 1/20 0.33
BRD4 O60885 1/20 0.33
PIK3CA P42336 1/20 0.33
PIK3CB P42338 1/20 0.33
MTOR P42345 1/20 0.33
PIK3CG P48736 1/20 0.33
KCNH2 Q12809 1/20 0.33
BRDT Q58F21 1/20 0.33
DHODH Q02127 1/20 0.33
GPR3 P46089 1/20 0.33
ESR1 P03372 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30035688 0.89 ALOX5 (0.46) ALOX5MAPTGGPS1PRKDCPTGES2
SCHEMBL10109135 0.89 ALOX5 (0.46) ALOX5MAPTGGPS1PRKDCPTGES2
SCHEMBL17550956 0.88 ALOX5 (0.45) ALOX5GGPS1PRKDCPTGES2CDK2
SCHEMBL25487990 0.86 PTGIR (0.41) ALOX5PTGIRMAPTESR2DHODH
SCHEMBL20277234 0.86 ALOX5 (0.59) ALOX5MAPTGGPS1PRKDCPTGES2
SCHEMBL25636279 0.86 PTGIR (0.41) ALOX5PTGIRMAPTPTGES2ESR2
SCHEMBL16883192 0.85 ALOX5 (0.55) ALOX5MAPTGGPS1PRKDCPTGES2
SCHEMBL75000 0.84 ALOX5 (0.59) ALOX5MAPTGGPS1PRKDCPTGES2
SCHEMBL30035488 0.84 ALOX5 (0.59) ALOX5MAPTGGPS1PRKDCPTGES2
SCHEMBL31593186 0.84 ALOX5 (0.59) ALOX5MAPTGGPS1PRKDCPTGES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230303537-A1 NITROGEN-CONTAINING COMPOUND, AND ELECTRONIC ELEMENT AND ELECTRONIC DEVICE THEREOF SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-09-28 US disclosed
US-20230303537-A1 NITROGEN-CONTAINING COMPOUND, AND ELECTRONIC ELEMENT AND ELECTRONIC DEVICE THEREOF SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230303537-A1 NITROGEN-CONTAINING COMPOUND, AND ELECTRONIC ELEMENT AND ELECTRONIC DEVICE THEREOF NPM1, NFE2L2, MNS1 ALOX5 2271/4885PTGIR 4481/4885MAPT 2129/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.