SCHEMBL16883192

SCHEMBL16883192

c1ccc2c(c1)oc1c(-c3ccc(Nc4ccc5c6ccccc6c6ccccc6c5c4)cc3)cccc12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.55
PRKDC P78527 4/20 0.43
GGPS1 O95749 1/20 0.41
PTGES2 Q9H7Z7 1/20 0.41
CDK2 P24941 1/20 0.38
ALDH1A1 P00352 4/20 0.36
KDM4E B2RXH2 4/20 0.36
HPGD P15428 3/20 0.36
MAPT P10636 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
ATM Q13315 1/20 0.36
EGFR P00533 1/20 0.36
DYRK1A Q13627 1/20 0.35
LMNA P02545 2/20 0.35
CASP3 P42574 2/20 0.35
SENP7 Q9BQF6 2/20 0.35
TSHR P16473 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31593186 0.91 ALOX5 (0.59) ALOX5PRKDCGGPS1PTGES2CDK2
SCHEMBL75000 0.91 ALOX5 (0.59) ALOX5PRKDCGGPS1PTGES2CDK2
SCHEMBL30035488 0.91 ALOX5 (0.59) ALOX5PRKDCGGPS1PTGES2CDK2
SCHEMBL10307237 0.90 ALOX5 (0.57) ALOX5PRKDCGGPS1PTGES2CDK2
SCHEMBL17986636 0.89 ALOX5 (0.58) ALOX5PRKDCGGPS1PTGES2CDK2
SCHEMBL29407300 0.88 ALOX5 (0.56) ALOX5PRKDCGGPS1PTGES2CDK2
SCHEMBL30215957 0.88 ALOX5 (0.56) ALOX5PRKDCGGPS1PTGES2CDK2
SCHEMBL75948 0.88 ALOX5 (0.56) ALOX5PRKDCGGPS1PTGES2CDK2
SCHEMBL10109886 0.87 ALOX5 (0.55) ALOX5PRKDCGGPS1PTGES2CDK2
SCHEMBL75955 0.87 ALOX5 (0.55) ALOX5PRKDCGGPS1PTGES2CDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10985325-B2 Aromatic amine derivative, and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2021-04-20 US disclosed
US-20180219157-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENTS, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-08-02 US disclosed
US-20180219157-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENTS, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-08-02 US disclosed
US-20150263292-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2015-09-17 US disclosed
US-20150263292-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2015-09-17 US disclosed
EP-2891653-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME Idemitsu Kosan Co., Ltd (JP) 2015-07-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150263292-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME RER1, H1-2, NAP1L1 ALOX5 2443/4885PRKDC 4736/4885GGPS1 4411/4885
US-10985325-B2 Aromatic amine derivative, and organic electroluminescent element using same RER1, H1-2, NAP1L1 ALOX5 2443/4885PRKDC 4736/4885GGPS1 4411/4885
US-20180219157-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENTS, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE L1CAM, LEF1, PIEZO1 ALOX5 2981/4885PRKDC 4865/4885GGPS1 2986/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.