Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.32 |
| ▸ | PPIA | P62937 | 4/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23788255 | 0.90 | MAPT (0.38) | MAPTHPGDSMN1; SMN2NPY1RNPY2R | |
| SCHEMBL23788253 | 0.89 | SMN1; SMN2 (0.43) | MAPTHPGDSMN1; SMN2NPY1RNPY2R | |
| SCHEMBL29318143 | 0.89 | SMN1; SMN2 (0.39) | MAPTHPGDSMN1; SMN2NPY1RNPY2R | |
| SCHEMBL26367242 | 0.88 | SMN1; SMN2 (0.38) | MAPTHPGDSMN1; SMN2NPY1RNPY2R | |
| SCHEMBL23788251 | 0.86 | MAPT (0.39) | MAPTHPGDSMN1; SMN2NPY1RNPY2R | |
| SCHEMBL13784389 | 0.86 | HPGD (0.36) | MAPTHPGDSMN1; SMN2NPY1RNPY2R | |
| SCHEMBL23788258 | 0.86 | MAPT (0.34) | MAPTHPGDSMN1; SMN2NPY1RNPY2R | |
| SCHEMBL2944987 | 0.85 | SMN1; SMN2 (0.40) | MAPTHPGDSMN1; SMN2NPY1RNPY2R | |
| SCHEMBL23788247 | 0.84 | HPGD (0.37) | MAPTHPGDSMN1; SMN2NPY1RNPY2R | |
| SCHEMBL29318080 | 0.83 | SMN1; SMN2 (0.36) | MAPTHPGDSMN1; SMN2NPY1RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3810115-B1 | PYRIDINE DERIVATIVES SUBSTITUTED BY HETEROCYCLIC RING AND AMINO GROUP | BASILEA PHARMACEUTICA INT AG ALLSCHWIL (CH) | 2024-07-17 | — | — | EP | disclosed |
| US-11771688-B2 | Pyridine derivatives substituted by heterocyclic ring and amino group | AMPLYX PHARMACEUTICALS, INC. (US) | 2023-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11771688-B2 | Pyridine derivatives substituted by heterocyclic ring and amino group | ERG28, PDXK, PAH | MAPT 1381/4885HPGD 164/4885SMN1; SMN2 3484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.