Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.38 |
| ▸ | PPIA | P62937 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23788247 | 0.91 | HPGD (0.37) | SMN1; SMN2HPGDMAPTNPY1RNPY2R | |
| SCHEMBL23788253 | 0.89 | SMN1; SMN2 (0.43) | SMN1; SMN2HPGDMAPTNPY1RNPY2R | |
| SCHEMBL13784389 | 0.87 | HPGD (0.36) | SMN1; SMN2HPGDMAPTNPY1RNPY2R | |
| SCHEMBL29318080 | 0.86 | SMN1; SMN2 (0.36) | SMN1; SMN2HPGDMAPTNPY1RNPY2R | |
| SCHEMBL2942827 | 0.86 | ALDH1A1 (0.36) | SMN1; SMN2HPGDMAPTNPY1RNPY2R | |
| SCHEMBL2300595 | 0.86 | LTA4H (0.43) | SMN1; SMN2HPGDMAPTNPY1RNPY2R | |
| SCHEMBL2300619 | 0.86 | LTA4H (0.43) | SMN1; SMN2HPGDMAPTNPY1RNPY2R | |
| SCHEMBL29318143 | 0.85 | SMN1; SMN2 (0.39) | SMN1; SMN2HPGDMAPTNPY1RNPY2R | |
| SCHEMBL26368792 | 0.85 | MAPT (0.39) | SMN1; SMN2HPGDMAPTNPY1RNPY2R | |
| SCHEMBL23788325 | 0.85 | ALDH1A1 (0.41) | SMN1; SMN2HPGDMAPTNPY1RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141171-A1 | PYRIDINE DERIVATIVE SUBSTITUTED WITH HETEROCYCLE AND PHOSPHONOAMINO AND ANTIFUNGAL AGENT CONTAINING THE SAME | Eisai R&D Management Co., Ltd. (JP) | 2010-01-06 | — | — | EP | disclosed |