SCHEMBL26375271

SCHEMBL26375271

Cc1c(OC(F)(F)F)ncc2ccccc12

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 11/20 0.41
KDM4E B2RXH2 1/20 0.40
GPR3 P46089 1/20 0.40
HPGD P15428 1/20 0.40
CYP2A6 P11509 3/20 0.37
CYP1A2 P05177 2/20 0.37
TSHR P16473 1/20 0.37
CYP17A1 P05093 1/20 0.36
ACP1 P24666 1/20 0.33
GRM4 Q14833 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25499806 0.80 CYP1A2 (0.47) KDM4EGPR3CYP2A6CYP1A2TSHR
SCHEMBL24910102 0.79 TRPM8 (0.43) TRPM8KDM4EGPR3HPGDCYP17A1
SCHEMBL2748882 0.79 TRPM8 (0.39) TRPM8
SCHEMBL21375123 0.77 KDM4E (0.41) KDM4EGPR3HPGDCYP2A6CYP1A2
SCHEMBL26375274 0.75 KDM4E (0.42) TRPM8KDM4EGPR3HPGDCYP2A6
SCHEMBL26375268 0.75 PLAU (0.41) HPGDCYP2A6CYP1A2ACP1
SCHEMBL26375264 0.71 NCEH1 (0.49) KDM4EHPGDCYP2A6CYP1A2TSHR
SCHEMBL12258315 0.71 GPR3 (0.50) TRPM8KDM4EGPR3HPGDCYP2A6
SCHEMBL24910101 0.69 P2RY2 (0.36) TRPM8HPGDCYP1A2ACP1
SCHEMBL12490240 0.68 KDM4E (0.47) KDM4EGPR3HPGDCYP2A6CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230309388-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230309388-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE OCIAD1, OCIAD2, SLCO4C1 TRPM8 652/4885KDM4E 1956/4885GPR3 2866/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.