SCHEMBL24910102

SCHEMBL24910102

CC(C)c1c(OC(F)(F)F)ncc2ccccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 8/20 0.43
HPGD P15428 1/20 0.37
KDM4E B2RXH2 1/20 0.37
GPR3 P46089 1/20 0.37
NCEH1 Q6PIU2 1/20 0.35
CYP17A1 P05093 1/20 0.34
CDK1 P06493 2/20 0.34
CDK4 P11802 2/20 0.34
CCNB1 P14635 2/20 0.34
CCND1 P24385 2/20 0.34
CCNE1 P24864 2/20 0.34
CDK2 P24941 2/20 0.34
ALDH1A1 P00352 1/20 0.33
KIF11 P52732 1/20 0.33
MAOA P21397 1/20 0.32
GRM4 Q14833 1/20 0.32
PDE9A O76083 1/20 0.32
PDE1A P54750 1/20 0.32
PDE1B Q01064 1/20 0.32
PDE1C Q14123 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26375271 0.79 TRPM8 (0.41) TRPM8HPGDKDM4EGPR3CYP17A1
SCHEMBL24910164 0.78 KDM4E (0.39) TRPM8HPGDKDM4EGPR3NCEH1
SCHEMBL24910101 0.76 P2RY2 (0.36) TRPM8HPGDALDH1A1KIF11GABRA1
SCHEMBL21871919 0.74 NCEH1 (0.52) TRPM8KDM4ENCEH1CYP17A1ALDH1A1
SCHEMBL13171265 0.73 KDM4E (0.44) TRPM8KDM4EGPR3NCEH1CDK1
SCHEMBL21871920 0.73 GPR3 (0.44) KDM4EGPR3NCEH1CDK1CDK4
SCHEMBL24910163 0.71 ALPL (0.37) KDM4EGPR3PDE9APDE1APDE1B
SCHEMBL19448396 0.69 KDM4E (0.40) TRPM8KDM4EGPR3NCEH1CDK1
SCHEMBL24713394 0.69 HRH4 (0.35)
SCHEMBL26375268 0.68 PLAU (0.41) HPGDALDH1A1KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4122934-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-01-25 EP disclosed