Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1412553 | 0.80 | TP53 (0.56) | TP53ALOX12KMT2ATSHRMAPK1 | |
| SCHEMBL14511339 | 0.76 | TSHR (0.49) | TP53ALOX12KMT2ATSHRMAPK1 | |
| SCHEMBL31123993 | 0.74 | TP53 (0.47) | TP53ALOX12KMT2ATSHRMAPT | |
| SCHEMBL1412510 | 0.73 | SMN1; SMN2 (0.47) | TP53ALOX12KMT2ATSHRMAPK1 | |
| SCHEMBL5280768 | 0.71 | MAOB (0.46) | TSHRMAPK1KDM4EALDH1A1MAOB | |
| SCHEMBL1412657 | 0.71 | TP53 (0.43) | TP53ALOX12KMT2ATSHRMAPK1 | |
| SCHEMBL21228619 | 0.71 | LMNA (0.46) | TP53KMT2ATSHRMAPK1MAPT | |
| SCHEMBL20143010 | 0.70 | TP53 (0.56) | TP53ALOX12KMT2ATSHRMAPK1 | |
| SCHEMBL1412525 | 0.70 | KMT2A (0.46) | TP53ALOX12KMT2ATSHRMAPK1 | |
| SCHEMBL14154666 | 0.69 | KMT2A (0.40) | KMT2ASMN1; SMN2KDM4EALDH1A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4252755-A2 | THERAPEUTIC COMPOUNDS | C4x Discovery Limited (GB) | 2023-10-04 | — | — | EP | disclosed |