Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 9/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | CHUK | O15111 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | AURKAIP1 | Q9NWT8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29811890 | 0.83 | VCAM1 (0.51) | VCAM1ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL23144363 | 0.83 | VCAM1 (0.51) | VCAM1ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL10383532 | 0.82 | VCAM1 (0.80) | VCAM1ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL26376297 | 0.78 | KMT2A (0.58) | VCAM1ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL10653026 | 0.76 | TDP1 (0.45) | VCAM1ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL5462361 | 0.75 | MAPT (0.64) | VCAM1ALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL11442100 | 0.75 | VCAM1 (0.61) | VCAM1ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL14419323 | 0.74 | TXNRD1 (0.52) | ALDH1A1MAPTHTTTSHR | |
| SCHEMBL12188688 | 0.74 | KMT2A (0.66) | VCAM1ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL11745901 | 0.74 | TSHR (0.54) | ALDH1A1KMT2AKDM4EMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11814373-B2 | Methods and compounds for restoring mutant p53 function | PMV PHARMACEUTICALS, INC. (US) | 2023-11-14 | — | — | US | disclosed |
| US-20230312539-A1 | METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION | PMV PHARMACEUTICALS, INC. | 2023-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230312539-A1 | METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION | TP53, TP53BP1, KRAS | VCAM1 3895/4885ALDH1A1 1538/4885KMT2A 2966/4885 |
| US-11814373-B2 | Methods and compounds for restoring mutant p53 function | TP53, TP53BP1, KRAS | VCAM1 3895/4885ALDH1A1 1538/4885KMT2A 2966/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.