Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10652013 | 0.89 | VCAM1 (0.47) | TDP1L3MBTL1ALDH1A1TSHRVCAM1 | |
| SCHEMBL10650928 | 0.79 | KMT2A (0.51) | TDP1L3MBTL1ALDH1A1TSHRVCAM1 | |
| SCHEMBL10650939 | 0.79 | KMT2A (0.51) | TDP1L3MBTL1ALDH1A1TSHRVCAM1 | |
| SCHEMBL10649978 | 0.77 | MAPK1 (0.46) | TDP1L3MBTL1ALDH1A1TSHRMAPT | |
| SCHEMBL10873353 | 0.76 | ALDH1A1 (0.47) | TDP1L3MBTL1ALDH1A1TSHRKMT2A | |
| SCHEMBL4815935 | 0.76 | TDP1 (0.54) | TDP1L3MBTL1ALDH1A1TSHRKMT2A | |
| SCHEMBL26376299 | 0.76 | VCAM1 (0.54) | ALDH1A1TSHRVCAM1KDM4EKMT2A | |
| SCHEMBL10654440 | 0.75 | MAPK1 (0.45) | TDP1L3MBTL1ALDH1A1TSHRKMT2A | |
| SCHEMBL10651980 | 0.71 | KMT2A (0.47) | TDP1L3MBTL1ALDH1A1VCAM1KDM4E | |
| SCHEMBL9811297 | 0.71 | KMT2A (0.47) | TDP1L3MBTL1ALDH1A1VCAM1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0197386-B1 | 2-(SUBSTITUTED SULFAMYL) DERIVATIVES OF 6-NITROBENZOIC ACID, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MERCK & CO. INC. (US) | 1988-11-02 | — | — | EP | claimed |