Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT1 | P42224 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2637806 | 0.82 | SLC22A12 (0.40) | RAB9ANPC1KMT2AMAPTHPGD | |
| SCHEMBL20914193 | 0.68 | SLC11A2 (0.49) | STAT1RAB9ASLC11A2NPC1SMN1; SMN2 | |
| SCHEMBL2637269 | 0.65 | SLC22A12 (0.41) | RAB9ANPC1SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL2637204 | 0.65 | NPC1 (0.43) | RAB9ANPC1SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL10055020 | 0.64 | NPC1 (0.94) | RAB9ARXFP1NPC1SMN1; SMN2KMT2A | |
| SCHEMBL4909326 | 0.64 | STAT1 (0.56) | STAT1RAB9ARXFP1NPC1SMN1; SMN2 | |
| SCHEMBL4720318 | 0.64 | MTNR1A (0.82) | RAB9ANPC1SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL2637246 | 0.63 | MAPK10 (0.41) | RAB9AKMT2AMAPTMEN1 | |
| SCHEMBL4251968 | 0.63 | RXFP1 (0.94) | RAB9ARXFP1NPC1SMN1; SMN2KMT2A | |
| SCHEMBL30862297 | 0.63 | RXFP1 (0.94) | RAB9ARXFP1NPC1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2438070-A1 | GLYCINE B ANTAGONISTS | Merz Pharma GmbH & Co. KGaA (DE) | 2012-04-11 | — | — | EP | claimed |
| WO-2010139483-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-12-09 | — | — | WO | claimed |