Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | PSD | A5PKW4 | 3/20 | 0.39 |
| ▸ | DHODH | Q02127 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2637207 | 0.92 | CNR2 (0.45) | MAPK10SLC22A12DHODHMEN1KMT2A | |
| SCHEMBL2638043 | 0.90 | MAPK10 (0.45) | MAPK10SLC22A12DHODHMEN1KMT2A | |
| SCHEMBL2637448 | 0.83 | NPC1 (0.46) | PSDMEN1KMT2ARAB9AMALT1 | |
| SCHEMBL2637918 | 0.83 | KMT2A (0.41) | MAPK10SLC22A12DHODHMEN1KMT2A | |
| SCHEMBL2637592 | 0.81 | MEN1 (0.45) | MEN1KMT2ARAB9AEGFR | |
| SCHEMBL2637493 | 0.80 | NHERF1 (0.46) | MEN1KMT2ARAB9AMAPTNPSR1 | |
| SCHEMBL2637533 | 0.80 | MAPT (0.50) | MEN1KMT2AMAPT | |
| SCHEMBL2637594 | 0.80 | MAT2A (0.37) | MEN1KMT2ARAB9AMAPTNPSR1 | |
| SCHEMBL2637204 | 0.79 | NPC1 (0.43) | MAPK10DHODHMEN1KMT2ARAB9A | |
| SCHEMBL2637260 | 0.77 | CNR2 (0.50) | MEN1KMT2ARAB9ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2438070-A1 | GLYCINE B ANTAGONISTS | Merz Pharma GmbH & Co. KGaA (DE) | 2012-04-11 | — | — | EP | disclosed |
| WO-2010139483-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-12-09 | — | — | WO | disclosed |