Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29740498 | 1.00 | ALDH1A1 (0.50) | ALDH1A1MAPTPOLBTP53HPGD | |
| SCHEMBL17755 | 0.85 | ALDH1A1 (0.51) | ALDH1A1MAPTPOLBHPGDLMNA | |
| SCHEMBL30482609 | 0.85 | ALDH1A1 (0.51) | ALDH1A1MAPTPOLBHPGDLMNA | |
| SCHEMBL1457582 | 0.83 | ALDH1A1 (0.50) | ALDH1A1MAPTPOLBTP53HPGD | |
| SCHEMBL499767 | 0.83 | MAPT (0.67) | ALDH1A1MAPTPOLBHPGDLMNA | |
| SCHEMBL610759 | 0.83 | ALDH1A1 (0.53) | ALDH1A1MAPTTP53LMNARECQL | |
| SCHEMBL27751160 | 0.83 | MAPT (0.67) | ALDH1A1MAPTPOLBHPGDLMNA | |
| SCHEMBL17193968 | 0.81 | CYP1A2 (0.67) | ALDH1A1MAPTPOLBHPGDLMNA | |
| SCHEMBL30494732 | 0.81 | CYP1A2 (0.67) | ALDH1A1MAPTPOLBHPGDLMNA | |
| SCHEMBL499583 | 0.81 | ALDH1A1 (0.47) | ALDH1A1MAPTPOLBHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118619823-A | Preparation method of 4-bromo-1-chloro-2- (4- (2-cyclopropyloxy ethoxy) benzyl) benzene | 杭州科巢生物科技有限公司 | 2024-09-10 | — | — | CN | claimed |
| CN-118546055-A | Preparation method of (1R, 3S, 5S) -3- (4- (5-bromo-2-chlorobenzyl) phenoxy) bicyclo [3.1.0] hexane | 山东科巢生物制药有限公司 | 2024-08-27 | — | — | CN | claimed |
| CN-118388436-A | Preparation method of englitz intermediate and englitz impurity | 江苏阿尔法药业股份有限公司 | 2024-07-26 | — | — | CN | claimed |
| CN-116262691-A | (5-bromo-2-chlorophenyl) (4-fluorophenyl) methanone | 苏州小栗医药科技有限公司 | 2023-06-16 | — | — | CN | claimed |
| EP-1881990-B1 | PROCESSES FOR PREPARING OF GLUCOPYRANOSYL-SUBSTITUTED BENZYL-BENZENE DERIVATIVES AND INTERMEDIATES THEREIN | BOEHRINGER INGELHEIM INT (DE) | 2016-02-17 | — | — | EP | claimed |
| US-9127034-B2 | Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivates and intermediates therein | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-09-08 | — | — | US | claimed |
| JP-4834080-B2 | — | — | 2011-12-07 | — | — | JP | claimed |
| US-20100240879-A1 | PROCESSES FOR PREPARING OF GLUCOPYRANOSYL-SUBSTITUTED BENZYL-BENZENE DERIVATES AND INTERMEDIATES THEREIN | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-23 | — | — | US | claimed |
| CN-101193903-A | Process for preparing glucopyranosyl-substituted benzylbenzene derivatives and intermediates thereof | BOEHRINGER INGELHEIM INT (DE) | 2008-06-04 | — | — | CN | claimed |
| EP-1881990-A1 | PROCESSES FOR PREPARING OF GLUCOPYRANOSYL-SUBSTITUTED BENZYL-BENZENE DERIVATIVES AND INTERMEDIATES THEREIN | Boehringer Ingelheim International GmbH (DE) | 2008-01-30 | — | — | EP | claimed |
| WO-2006120208-A1 | PROCESSES FOR PREPARING OF GLUCOPYRANOSYL-SUBSTITUTED BENZYL-BENZENE DERIVATIVES AND INTERMEDIATES THEREIN | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-11-16 | — | — | WO | claimed |
| US-20060258749-A1 | Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivatives and intermediates therein | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-11-16 | — | — | US | claimed |
| WO-2025056984-A1 | A NOVEL PROCESS FOR THE PREPARATION OF BEXAGLIFLOZIN A SGLT2 INHIBITOR AND ITS INTERMEDIATES THEREOF | VIJAYASRI ORGANICS PRIVATE LIMITED (IN) | 2025-03-20 | — | — | WO | disclosed |
| CN-118619823-A | Preparation method of 4-bromo-1-chloro-2- (4- (2-cyclopropyloxy ethoxy) benzyl) benzene | 杭州科巢生物科技有限公司 | 2024-09-10 | — | — | CN | disclosed |
| CN-118546055-A | Preparation method of (1R, 3S, 5S) -3- (4- (5-bromo-2-chlorobenzyl) phenoxy) bicyclo [3.1.0] hexane | 山东科巢生物制药有限公司 | 2024-08-27 | — | — | CN | disclosed |
| CN-118388436-A | Preparation method of englitz intermediate and englitz impurity | 江苏阿尔法药业股份有限公司 | 2024-07-26 | — | — | CN | disclosed |
| CN-101193903-A | Process for preparing glucopyranosyl-substituted benzylbenzene derivatives and intermediates thereof | BOEHRINGER INGELHEIM INT (DE) | 2008-06-04 | — | — | CN | disclosed |
| EP-1881990-A1 | PROCESSES FOR PREPARING OF GLUCOPYRANOSYL-SUBSTITUTED BENZYL-BENZENE DERIVATIVES AND INTERMEDIATES THEREIN | Boehringer Ingelheim International GmbH (DE) | 2008-01-30 | — | — | EP | disclosed |
| WO-2006120208-A1 | PROCESSES FOR PREPARING OF GLUCOPYRANOSYL-SUBSTITUTED BENZYL-BENZENE DERIVATIVES AND INTERMEDIATES THEREIN | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-11-16 | — | — | WO | disclosed |
| US-20060258749-A1 | Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivatives and intermediates therein | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060258749-A1 | Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivatives and intermediates therein | UGGT1, B3GAT3, B4GALT1 | ALDH1A1 273/4885MAPT 4699/4885POLB 1080/4885 |
| US-20100240879-A1 | PROCESSES FOR PREPARING OF GLUCOPYRANOSYL-SUBSTITUTED BENZYL-BENZENE DERIVATES AND INTERMEDIATES THEREIN | UGGT1, B3GAT3, B4GALT1 | ALDH1A1 200/4885MAPT 4669/4885POLB 1337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.