⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetaldehyde SCHEMBL4115602 | 0.91 | ALDH1A1 (0.42) | — | |
| Propionic Acid SCHEMBL23467114 | 0.89 | FFAR3 (0.43) | — | |
| SCHEMBL3181863 | 0.82 | ALDH1A1 (0.43) | — | |
| SCHEMBL28941963 | 0.80 | ALDH1A1 (0.50) | — | |
| SCHEMBL18026348 | 0.79 | ALDH1A1 (0.47) | — | |
| SCHEMBL3318249 | 0.79 | SMN1; SMN2 (0.44) | — | |
| SCHEMBL29261236 | 0.79 | POLB (0.40) | — | |
| SCHEMBL18343107 | 0.77 | L3MBTL1 (0.50) | — | |
| SCHEMBL2858623 | 0.77 | KDM4C (0.50) | — | |
| SCHEMBL19171550 | 0.77 | SMN1; SMN2 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 361 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4142732-B1 | METHODS OF USE FOR PYRIMIDINES AS FERROPORTIN INHIBITORS | GLOBAL BLOOD THERAPEUTICS INC (US) | 2026-04-22 | — | — | EP | disclosed |
| US-12472166-B2 | Inhibition of mycobacterial type VII secretion | STICHTING VUMC (NL) | 2025-11-18 | — | — | US | disclosed |
| US-20250214932-A1 | T-TYPE CALCIUM CHANNEL MODULATORS COMPRISING AN AZASPIRONONANE CORE AND METHODS OF USE THEREOF | PRAXIS PRECISION MEDICINES, INC. | 2025-07-03 | — | — | US | disclosed |
| US-20250215011-A1 | T-TYPE CALCIUM CHANNEL MODULATORS COMPRISING A DIAZASPIROHEPTANE CORE AND METHODS OF USE THEREOF | PRAXIS PRECISION MEDICINES, INC. | 2025-07-03 | — | — | US | disclosed |
| US-20250213558-A1 | T-TYPE CALCIUM CHANNEL MODULATORS COMPRISING A PIPERAZINE OR 1,4-DIAZEPANE CORE AND METHODS OF USE THEREOF | PRAXIS PRECISION MEDICINES, INC. | 2025-07-03 | — | — | US | disclosed |
| EP-3340988-B1 | ION CHANNEL INHIBITORY COMPOUNDS, PHARMACEUTICAL FORMULATIONS AND USES | AFASCI INC (US) | 2025-04-09 | — | — | EP | disclosed |
| US-20250109122-A1 | CYCLOALKYL PYRIMIDINES AS FERROPORTIN INHIBITORS | GLOBAL BLOOD THERAPEUTICS INC (US) | 2025-04-03 | — | — | US | disclosed |
| EP-4504188-A1 | T-TYPE CALCIUM CHANNEL MODULATORS COMPRISING AN AZASPIROHEPTANE CORE AND METHODS OF USE THEREOF | Praxis Precision Medicines, Inc. (US) | 2025-02-12 | — | — | EP | disclosed |
| EP-4504187-A1 | T-TYPE CALCIUM CHANNEL MODULATORS COMPRISING AN AZASPIRONONANE CORE AND METHODS OF USE THEREOF | Praxis Precision Medicines, Inc. (US) | 2025-02-12 | — | — | EP | disclosed |
| EP-4504170-A2 | T-TYPE CALCIUM CHANNEL MODULATORS COMPRISING A DIAZASPIROHEPTANE CORE AND METHODS OF USE THEREOF | Praxis Precision Medicines, Inc. (US) | 2025-02-12 | — | — | EP | disclosed |
| WO-1999006434-A1 | 4-AMINO-PHENYLALANINE TYPE COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARMACEUTICALS INC. (US) | 1999-02-11 | — | — | WO | disclosed |
| US-5618808-A | Benzothiazepine and benzoxazepine derivatives as cholecystokinin receptor antagonists | PFIZER, INC. (US) | 1997-04-08 | — | — | US | disclosed |
| EP-0657454-A1 | Imidazopyridazines being angiotensin II antagonists | MERCK PATENT GmbH (DE) | 1995-06-14 | — | — | EP | disclosed |
| EP-0648213-A1 | BENZOTHIAZEPINE AND BENZOXAZEPINE DERIVATIVES AS CHOLECYSTOKININ RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 1995-04-19 | — | — | EP | disclosed |
| WO-1994001421-A1 | BENZOTHIAZEPINE AND BENZOXAZEPINE DERIVATIVES AS CHOLECYSTOKININ RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 1994-01-20 | — | — | WO | disclosed |
| US-4988814-A | Antidepressants and/or anxiolytic agents | AMERICAN HOME PRODUCTS CORP. (US) | 1991-01-29 | — | — | US | disclosed |
| EP-0395313-A2 | Tertiary alkyl functionalized piperazine derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1990-10-31 | — | — | EP | disclosed |
| EP-0221410-B1 | BISTHIOL PHOSPHATES, PROCESS FOR THEIR PREPARATION, THEIR USE AS PESTICIDES AND AGENTS THEREFOR | BASF Aktiengesellschaft (DE) | 1989-04-19 | — | — | EP | disclosed |
| US-4775666-A | INSECTS, ACARINA, NEMATODES | BASF AKTIENGESELLSCHAFT (DE) | 1988-10-04 | — | — | US | disclosed |
| EP-0221410-A1 | Bisthiol phosphates, process for their preparation, their use as pesticides and agents therefor | BASF Aktiengesellschaft (DE) | 1987-05-13 | — | — | EP | disclosed |