Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.50 |
| ▸ | SHMT1 | P34896 | 10/20 | 0.40 |
| ▸ | SHMT2 | P34897 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6314323 | 0.78 | KDM4C (0.47) | KDM4CSHMT1SHMT2ALDH1A1TSHR | |
| SCHEMBL2081025 | 0.78 | KDM4C (0.52) | KDM4CSHMT1SHMT2ALDH1A1SMN1; SMN2 | |
| SCHEMBL6314328 | 0.78 | KDM4C (0.47) | KDM4CSHMT1SHMT2ALDH1A1TSHR | |
| SCHEMBL484144 | 0.77 | CNR2 (0.36) | KDM4CALDH1A1SMN1; SMN2MAPTEGFR | |
| SCHEMBL1057511 | 0.77 | KDM4C (0.34) | KDM4CALDH1A1SMN1; SMN2TSHREGFR | |
| SCHEMBL14382979 | 0.77 | KDM4C (0.47) | KDM4CSHMT1SHMT2ALDH1A1TSHR | |
| SCHEMBL263784 | 0.77 | — | — | |
| SCHEMBL13240549 | 0.76 | KDM4C (0.45) | KDM4CSHMT1SHMT2ALDH1A1TSHR | |
| SCHEMBL15680104 | 0.76 | ALDH1A1 (0.52) | KDM4CSHMT1SHMT2ALDH1A1TSHR | |
| SCHEMBL7165759 | 0.76 | SMN1; SMN2 (0.46) | KDM4CALDH1A1SMN1; SMN2TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120129793-A1 | Antimicrobial Polyether and Polyol Compounds | NOVABAY PHARMACEUTICALS, INC. | 2012-05-24 | — | — | US | disclosed |
| EP-1606321-B1 | AZLACTONE PHOTOINIFERTERS FOR RADICAL POLYMERIZATION | 3M INNOVATIVE PROPERTIES CO (US) | 2010-01-20 | — | — | EP | disclosed |
| EP-1606321-B1 | AZLACTONE PHOTOINIFERTERS FOR RADICAL POLYMERIZATION | 3M INNOVATIVE PROPERTIES CO (US) | 2010-01-20 | — | — | EP | disclosed |
| EP-2046726-B1 | PREPARATION OF (2R,3R)-3-(3-METHOXYPHENYL)-N,N,2-TRIMETHYLPENTANAMINE | JANSSEN PHARMACEUTICA NV (BE) | 2010-01-20 | — | — | EP | disclosed |
| US-7625917-B2 | S-o-(phenylaminocarbonyl)phenyl-substituted, especially with a quaternary onium group; enhanced antiviral activity and better reactivity with zinc finger moieties, particularly, the zinc finger on HIV-1's NCp7 nucleocapsid protein | TURPIN JAMES A | 2009-12-01 | — | — | US | disclosed |
| CN-100526357-C | Ring-opened azlactone chain transfer agents for free radical polymerization | 3M INNOVATIVE PROPERTIES CO (US) | 2009-08-12 | — | — | CN | disclosed |
| US-7557177-B2 | Ring-opened azlactone initiators for atom transfer radical polymerization | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2009-07-07 | — | — | US | disclosed |
| EP-1622952-B1 | AZLACTONE CHAIN TRANSFER AGENTS FOR RADICAL POLYMERIZATION | 3M INNOVATIVE PROPERTIES CO (US) | 2009-01-14 | — | — | EP | disclosed |
| EP-1569966-B1 | RING-OPENED AZLACTONE INITIATORS FOR ATOM TRANSFER RADICAL POLYMERIZATION | 3M INNOVATIVE PROPERTIES CO (US) | 2008-05-28 | — | — | EP | disclosed |
| US-20080027210-A1 | RING-OPENED AZLACTONE INITIATORS FOR ATOM TRANSFER RADICAL POLYMERIZATION | 3M INNOVATIVE PROPERTIES COMPANY | 2008-01-31 | — | — | US | disclosed |
| WO-2004052944-A1 | RING-OPENED AZLACTONE INITIATORS FOR ATOM TRANSFER RADICAL POLYMERIZATION | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2004-06-24 | — | — | WO | disclosed |
| US-6753391-B1 | XANTHATE, THIOXANTHATE, OR DITHIOESTER DERIVATIVES FOR TELECHELIC POLYMERS; ADDITION POLYMERIZATION | 3M INNOVATIVE PROPERTIES COMPANY | 2004-06-22 | — | — | US | disclosed |
| US-20040116633-A1 | Ring-opened azlactone initiators for atom transfer radical polymerization | 3M INNOVATIVE PROPERTIES COMPANY | 2004-06-17 | — | — | US | disclosed |
| US-20040116616-A1 | Azlactone initiators for atom transfer radical polymerization | 3M INNOVATIVE PROPERTIES COMPANY | 2004-06-17 | — | — | US | disclosed |
| US-6747104-B1 | PHOTOINIFERTERS FOR RADICAL POLYMERIZATION PROCESSES AND TELECHELIC POLYMERS MADE THEREBY. | 3M INNOVATIVE PROPERTIES COMPANY | 2004-06-08 | — | — | US | disclosed |
| US-6706729-B1 | A METHOD FOR DISSOCIATING A METAL ION FROM A ZINC FINGER-CONTAINING PROTEIN; INHIBITING VIRUS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2004-03-16 | — | — | US | disclosed |
| WO-2003063874-A1 | CONDENSED HETEROCYCLIC COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-08-07 | — | — | WO | disclosed |
| EP-1087941-A2 | THIOLESTERS AND USES THEREOF | THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, Department of Health and Human Services (US) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999065871-A2 | THIOLESTERS AND USES THEREOF | THE GOVERNMENT OF THE UNITED STATES OF AMERICA REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1999-12-23 | — | — | WO | disclosed |
| US-4055663-A | Halogenated acylamino acids as fungicides | NATIONAL PATENT DEVELOPMENT CORPORATION (US) | 1977-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120129793-A1 | Antimicrobial Polyether and Polyol Compounds | POLR1C, DPM1, PRF1 | KDM4C 4520/4885SHMT1 4706/4885SHMT2 4551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.