Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | STAT3 | P40763 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | FBP1 | P09467 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25769880 | 0.86 | NLRP3 (0.61) | NLRP3SMN1; SMN2LMNAHTTKMT2A | |
| SCHEMBL25293876 | 0.85 | SMN1; SMN2 (0.45) | NLRP3SMN1; SMN2LMNAHTTKMT2A | |
| SCHEMBL25769883 | 0.80 | NLRP3 (0.51) | NLRP3SMN1; SMN2LMNAHTTKMT2A | |
| SCHEMBL26378655 | 0.79 | SMN1; SMN2 (0.57) | NLRP3SMN1; SMN2LMNAHTTKMT2A | |
| SCHEMBL6101644 | 0.79 | SMN1; SMN2 (0.64) | NLRP3SMN1; SMN2LMNAHTTKMT2A | |
| SCHEMBL6099937 | 0.78 | ALDH1A1 (0.65) | SMN1; SMN2LMNAHTTKMT2AEPHX2 | |
| SCHEMBL25769888 | 0.76 | LMNA (0.57) | NLRP3SMN1; SMN2LMNAHTTKMT2A | |
| SCHEMBL6098990 | 0.75 | SMN1; SMN2 (0.60) | NLRP3SMN1; SMN2LMNAHTTKMT2A | |
| SCHEMBL6100978 | 0.74 | KDM4E (0.65) | NLRP3SMN1; SMN2LMNAHTTKMT2A | |
| SCHEMBL6100235 | 0.74 | BCHE (0.65) | SMN1; SMN2LMNAHTTKMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230312474-A1 | PHENOL DERIVATIVE | Sumitomo Pharma Co., Ltd. (JP) | 2023-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230312474-A1 | PHENOL DERIVATIVE | TYR, NCOR1, BET1 | NLRP3 599/4885SMN1; SMN2 2949/4885LMNA 1203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.