Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 14/20 | 0.59 |
| ▸ | SLC5A1 | P13866 | 8/20 | 0.59 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 2/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2870718 | 1.00 | SLC5A2 (0.59) | SLC5A2SLC5A1ALKHTR2ASLC6A4 | |
| SCHEMBL29882671 | 1.00 | SLC5A2 (0.59) | SLC5A2SLC5A1ALKHTR2ASLC6A4 | |
| SCHEMBL29740488 | 1.00 | SLC5A2 (0.59) | SLC5A2SLC5A1ALKHTR2ASLC6A4 | |
| SCHEMBL2638119 | 1.00 | SLC5A2 (0.59) | SLC5A2SLC5A1ALKHTR2ASLC6A4 | |
| SCHEMBL2638466 | 0.93 | SLC5A2 (0.51) | SLC5A2SLC5A1HTR2ASLC6A4KCNH2 | |
| SCHEMBL181205 | 0.90 | SLC5A2 (0.48) | SLC5A2SLC5A1HTR2ASLC6A4KCNH2 | |
| SCHEMBL30830341 | 0.88 | SLC5A2 (0.61) | SLC5A2SLC5A1PDE2APDE10AHRH3 | |
| SCHEMBL19189964 | 0.87 | SLC5A2 (0.60) | SLC5A2SLC5A1PDE2APDE10AHRH3 | |
| SCHEMBL3465613 | 0.86 | SLC5A2 (0.59) | SLC5A2SLC5A1PDE2APDE10AHRH3 | |
| SCHEMBL14949150 | 0.86 | SLC5A2 (0.59) | SLC5A2SLC5A1PDE2APDE10AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486837-A | 4- (4-chloro-3- { [4- (tetrahydrofuran-3-oxy) phenyl ] methyl } phenoxy) butane-1-ol compound and preparation method thereof | 湖北省宏源药业科技股份有限公司 | 2024-02-02 | — | — | CN | claimed |
| CN-117299223-A | Synthetic method of intermediate for preparing enggliflozin | 沧州那瑞化学科技有限公司 | 2023-12-29 | — | — | CN | claimed |
| CN-113480497-B | Synthetic method of empagliflozin key intermediate | 山东铂源药业股份有限公司 | 2023-02-28 | — | — | CN | claimed |
| WO-2023005587-A1 | SYNTHESIS METHOD FOR EMPAGLIFLOZIN KEY INTERMEDIATE | 山东铂源药业股份有限公司 | 2023-02-02 | — | — | WO | claimed |
| CN-113563318-A | Synthesis method of engagliflozin | 山东铂源药业有限公司 | 2021-10-29 | — | — | CN | claimed |
| CN-113480497-A | Synthesis method of empagliflozin key intermediate | 山东铂源药业有限公司 | 2021-10-08 | — | — | CN | claimed |
| CN-112641773-A | Composition containing heterocyclic compound and use thereof | 黄泳华 | 2021-04-13 | — | — | CN | claimed |
| CN-111265512-A | Composition containing a mixture of benzyl benzene derivatives and uses thereof | 黄泳华 | 2020-06-12 | — | — | CN | claimed |
| CN-107556302-B | Method for preparing empagliflozin | 中国医药集团总公司四川抗菌素工业研究所 | 2019-12-13 | — | — | CN | claimed |
| EP-1881990-B1 | PROCESSES FOR PREPARING OF GLUCOPYRANOSYL-SUBSTITUTED BENZYL-BENZENE DERIVATIVES AND INTERMEDIATES THEREIN | BOEHRINGER INGELHEIM INT (DE) | 2016-02-17 | — | — | EP | claimed |
| US-9127034-B2 | Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivates and intermediates therein | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-09-08 | — | — | US | claimed |
| JP-4834080-B2 | — | — | 2011-12-07 | — | — | JP | claimed |
| US-20100240879-A1 | PROCESSES FOR PREPARING OF GLUCOPYRANOSYL-SUBSTITUTED BENZYL-BENZENE DERIVATES AND INTERMEDIATES THEREIN | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-23 | — | — | US | claimed |
| EP-1881990-A1 | PROCESSES FOR PREPARING OF GLUCOPYRANOSYL-SUBSTITUTED BENZYL-BENZENE DERIVATIVES AND INTERMEDIATES THEREIN | Boehringer Ingelheim International GmbH (DE) | 2008-01-30 | — | — | EP | claimed |
| WO-2006120208-A1 | PROCESSES FOR PREPARING OF GLUCOPYRANOSYL-SUBSTITUTED BENZYL-BENZENE DERIVATIVES AND INTERMEDIATES THEREIN | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-11-16 | — | — | WO | claimed |
| US-20060258749-A1 | Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivatives and intermediates therein | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-11-16 | — | — | US | claimed |
| CN-117486837-A | 4- (4-chloro-3- { [4- (tetrahydrofuran-3-oxy) phenyl ] methyl } phenoxy) butane-1-ol compound and preparation method thereof | 湖北省宏源药业科技股份有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-117299223-A | Synthetic method of intermediate for preparing enggliflozin | 沧州那瑞化学科技有限公司 | 2023-12-29 | — | — | CN | disclosed |
| WO-2006120208-A1 | PROCESSES FOR PREPARING OF GLUCOPYRANOSYL-SUBSTITUTED BENZYL-BENZENE DERIVATIVES AND INTERMEDIATES THEREIN | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-11-16 | — | — | WO | disclosed |
| US-20060258749-A1 | Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivatives and intermediates therein | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060258749-A1 | Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivatives and intermediates therein | UGGT1, B3GAT3, B4GALT1 | SLC5A2 120/4885SLC5A1 111/4885ALK 2339/4885 |
| US-20100240879-A1 | PROCESSES FOR PREPARING OF GLUCOPYRANOSYL-SUBSTITUTED BENZYL-BENZENE DERIVATES AND INTERMEDIATES THEREIN | UGGT1, B3GAT3, B4GALT1 | SLC5A2 123/4885SLC5A1 85/4885ALK 2147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.