SCHEMBL2637585

SCHEMBL2637585

CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@](O)(C(N)=O)CC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 0.67

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ USP2 O75604 2/20 0.67
▸ CYP46A1 Q9Y6A2 2/20 0.67
▸ LMNA P02545 1/20 0.67
▸ ABCB1 P08183 1/20 0.67
▸ OSBP P22059 1/20 0.67
▸ RORC P51449 1/20 0.67
▸ OSBP2 Q969R2 1/20 0.67
▸ POLA1 P09884 1/20 0.63
▸ GRIN1 Q05586 12/20 0.61
▸ GRIN2B Q13224 12/20 0.61
▸ GRIN2A Q12879 10/20 0.61
▸ SRD5A1 P18405 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2221515 1.00 USP2 (0.67) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL27963051 0.92 USP2 (0.68) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL27963054 0.92 USP2 (0.68) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL27975861 0.92 USP2 (0.68) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL2638134 0.92 USP2 (0.68) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL6060845 0.92 USP2 (0.68) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL22194040 0.91 USP2 (0.65) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL22194041 0.91 USP2 (0.65) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL8426935 0.91 USP2 (0.67) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL18631920 0.90 USP2 (0.63) USP2CYP46A1LMNAABCB1OSBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2780031-A1 GLUCAGON SUPERFAMILY PEPTIDES EXHIBITING GLUCOCORTICOID RECEPTOR ACTIVITY Indiana University Research and Technology Corporation (US) 2014-09-24 — — EP disclosed
WO-2013074910-A1 GLUCAGON SUPERFAMILY PEPTIDES EXHIBITING GLUCOCORTICOID RECEPTOR ACTIVITY INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2013-05-23 — — WO disclosed
EP-2569000-A1 GLUCAGON SUPERFAMILY PEPTIDES EXHIBITING NUCLEAR HORMONE RECEPTOR ACTIVITY Indiana University Research and Technology Corporation (US) 2013-03-20 — — EP disclosed
WO-2011143209-A1 GLUCAGON SUPERFAMILY PEPTIDES EXHIBITING NUCLEAR HORMONE RECEPTOR ACTIVITY INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2011-11-17 — — WO disclosed
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