SCHEMBL22194041

SCHEMBL22194041

CC(C)CCCC(C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@](O)(C(=O)C(C)N)CC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 0.65

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ USP2 O75604 2/20 0.65
▸ CYP46A1 Q9Y6A2 2/20 0.65
▸ LMNA P02545 1/20 0.65
▸ ABCB1 P08183 1/20 0.65
▸ OSBP P22059 1/20 0.65
▸ RORC P51449 1/20 0.65
▸ OSBP2 Q969R2 1/20 0.65
▸ POLA1 P09884 1/20 0.61
▸ GRIN1 Q05586 12/20 0.60
▸ GRIN2B Q13224 12/20 0.60
▸ GRIN2A Q12879 10/20 0.59
▸ SRD5A1 P18405 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22194040 1.00 USP2 (0.65) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL2637585 0.91 USP2 (0.67) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL2221515 0.91 USP2 (0.67) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL6060845 0.90 USP2 (0.68) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL27963051 0.90 USP2 (0.68) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL27963054 0.90 USP2 (0.68) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL2638134 0.90 USP2 (0.68) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL27975861 0.90 USP2 (0.68) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL8426935 0.90 USP2 (0.67) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL18631920 0.88 USP2 (0.63) USP2CYP46A1LMNAABCB1OSBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4701639-A1 MOLECULES TARGETING INFECTED TISSUES AND METHODS OF USE THEREOF University of Tartu (EE) 2026-03-04 — — EP disclosed
WO-2024249553-A1 MOLECULES TARGETING INFECTED TISSUES AND METHODS OF USE THEREOF UNIVERSITY OF TARTU (EE) 2024-12-05 — — WO disclosed
EP-4429633-A1 NANOPARTICULATE FORMULATION Newimmune II, LLC (US) 2024-09-18 — — EP disclosed
EP-4247493-A1 METHODS AND COMPOSITIONS COMPRISING CATIONIC LIPIDS FOR IMMUNOTHERAPY BY DIRECT TUMOR INJECTION PDS Biotechnology Corporation (US) 2023-09-27 — — EP disclosed
WO-2023062353-A1 NANOPARTICULATE FORMULATION NEWIMMUNE II, LLC (US) 2023-04-20 — — WO disclosed
WO-2022109391-A1 METHODS AND COMPOSITIONS COMPRISING CATIONIC LIPIDS FOR IMMUNOTHERAPY BY DIRECT TUMOR INJECTION PDS BIOTECHNOLOGY CORPORATION (US) 2022-05-27 — — WO disclosed
US-10709664-B2 Nanolipogel comprising a polymeric matrix and a lipid shell YALE UNIVERSITY (US) 2020-07-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10709664-B2 Nanolipogel comprising a polymeric matrix and a lipid shell LIPA, CD44, ABCB4 USP2 1111/4885CYP46A1 464/4885LMNA 4214/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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