SCHEMBL2221515

SCHEMBL2221515

CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4CC(O)(C(N)=O)CC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 0.67

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ USP2 O75604 2/20 0.67
▸ CYP46A1 Q9Y6A2 2/20 0.67
▸ LMNA P02545 1/20 0.67
▸ ABCB1 P08183 1/20 0.67
▸ OSBP P22059 1/20 0.67
▸ RORC P51449 1/20 0.67
▸ OSBP2 Q969R2 1/20 0.67
▸ POLA1 P09884 1/20 0.63
▸ GRIN1 Q05586 12/20 0.61
▸ GRIN2B Q13224 12/20 0.61
▸ GRIN2A Q12879 10/20 0.61
▸ SRD5A1 P18405 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2637585 1.00 USP2 (0.67) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL27963051 0.92 USP2 (0.68) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL27963054 0.92 USP2 (0.68) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL27975861 0.92 USP2 (0.68) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL2638134 0.92 USP2 (0.68) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL6060845 0.92 USP2 (0.68) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL22194040 0.91 USP2 (0.65) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL22194041 0.91 USP2 (0.65) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL8426935 0.91 USP2 (0.67) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL18631920 0.90 USP2 (0.63) USP2CYP46A1LMNAABCB1OSBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 256 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024144348-A1 VACCINE COMPOSITION COMPRISING IONIC COMPLEX OF CATIONIC MOLECULAR TRANSPORTER AND MRNA 주식회사 바이오파마 2024-07-04 — — WO claimed
CN-118201605-A POEGMA-based lipid nanoparticles 杜克大学 2024-06-14 — — CN claimed
US-20240165222-A1 VACCINE COMPOSITION FOR PREVENTING SARS-COV-2 EYEGENE INC. (KR) 2024-05-23 — — US claimed
US-20240148897-A1 COMPOSITION FOR IN VIVO DELIVERY OF RNA AND PREPERATION METHOD THEREFOR EYEGENE INC. (KR) 2024-05-09 — — US claimed
EP-4356933-A1 COMPOSITION FOR DELIVERING MODIFIED NUCLEIC ACID-CONTAINING MRNA Eyegene, Inc. (KR) 2024-04-24 — — EP claimed
WO-2024054020-A1 COMPOSITION FOR DELIVERING MODIFIED NUCLEIC ACID-CONTAINING MRNA 아이진 주식회사 2024-03-14 — — WO claimed
EP-4306132-A1 COMPOSITION FOR IN VIVO DELIVERY OF RNA AND PREPARATION METHOD THEREFOR Eyegene Inc. (KR) 2024-01-17 — — EP claimed
EP-4306126-A1 VACCINE COMPOSITION FOR PREVENTING SARS-COV-2 Eyegene Inc. (KR) 2024-01-17 — — EP claimed
CN-116940376-A Vaccine composition for preventing SARS-COV-2 艾金株式会社 2023-10-24 — — CN claimed
CN-115957382-A Medical instrument for interventional therapy 凯诺威医疗科技(武汉)有限公司 2023-04-14 — — CN claimed
US-11406742-B2 Coating for intraluminal expandable catheter providing contact transfer of drug micro-reservoirs M.A. Med Alliance SA (CH) 2022-08-09 — — US claimed
US-20220054370-A1 MULTILAYERED CATIONIC LIPOSOME FOR ENHANCING SKIN ABSORPTION AND PREPARATION METHOD THEREFOR COSMAX, INC. (KR) 2022-02-24 — — US claimed
EP-2839015-B1 LIPIDATED GLYCOSAMINOGLYCAN PARTICLES FOR THE DELIVERY OF NUCLEIC ACIDS UNIV RAMOT (IL) 2020-04-29 — — EP claimed
CN-110179753-A Nano medication delivery system and its preparation and the application of a kind of targeting brain tumor and its tumor stem cell 上海市同仁医院 2019-08-30 — — CN claimed
CN-102989007-B The extensive method preparing injection Midkine antisense oligonucleotide nano liposome CENTRAL HOSPITAL, HUZHOU CITY (CN) 2015-12-16 — — CN claimed
CN-104906567-A Application of ligand-mediated dendritic cell targeting Texosomes bionic body as tumor vaccine UNIV SHENYANG PHARMACEUTICAL 2015-09-16 — — CN claimed
EP-2839015-A1 LIPIDATED GLYCOSAMINOGLYCAN PARTICLES FOR THE DELIVERY OF NUCLEIC ACIDS Ramot at Tel-Aviv University Ltd. (IL) 2015-02-25 — — EP claimed
CN-104043133-A Gene medicine for targeted inhibition of lung cancer cells and preparation method thereof GUANGZHOU JKTT CO LTD 2014-09-17 — — CN claimed
CN-104043134-A Nano-liposome as well as preparation method and application thereof GUANGZHOU JKTT CO LTD 2014-09-17 — — CN claimed
WO-2013156989-A1 LIPIDATED GLYCOSAMINOGLYCAN PARTICLES FOR THE DELIVERY OF NUCLEIC ACIDS RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2013-10-24 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240165222-A1 VACCINE COMPOSITION FOR PREVENTING SARS-COV-2 ACE2, SARS1, RBM22 USP2 158/4885CYP46A1 1357/4885LMNA 2735/4885
US-20240148897-A1 COMPOSITION FOR IN VIVO DELIVERY OF RNA AND PREPERATION METHOD THEREFOR RTCB, RRP1B, PRPF6 USP2 2649/4885CYP46A1 733/4885LMNA 138/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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