SCHEMBL2639752

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7420409	0.92	HTR1A (0.53)	F10HTR1AHTR1DHTR2CNPC1
	SCHEMBL2640158	0.89	F10 (0.52)	F10HTR1AHTR1DHTR2CPRSS1
	SCHEMBL2639963	0.89	HTR1A (0.44)	F10HTR1AHTR1DHTR2CPLAU
	SCHEMBL6216925	0.89	ITGB3 (0.49)	F10HTR1AHTR1DHTR2CCHRM4
	SCHEMBL6215027	0.83	CHRM4 (0.41)	CHRM4CA12CA1CA2MMP2
	SCHEMBL6212650	0.83	F10 (0.51)	F10HTR1AHTR1DHTR2CF2
	SCHEMBL2640127	0.82	HTR1A (0.48)	F10HTR1AHTR1DHTR2CF2
	SCHEMBL2640150	0.81	HTR1A (0.53)	F10HTR1AHTR1DHTR2CPRSS1
	SCHEMBL2639545	0.81	HTR1A (0.50)	F10HTR1AHTR1DHTR2CF2
	SCHEMBL2640085	0.81	HTR1A (0.47)	F10HTR1AHTR1DHTR2CPRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.