Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | HTR1D | P28221 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | F10 | P00742 | 5/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.45 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2640158 | 0.95 | F10 (0.52) | HTR1AHTR1DHTR2CF10TBXA2R | |
| SCHEMBL2639752 | 0.92 | F10 (0.47) | HTR1AHTR1DHTR2CF10ITGB3 | |
| SCHEMBL6216925 | 0.89 | ITGB3 (0.49) | HTR1AHTR1DHTR2CF10ITGB3 | |
| SCHEMBL6212650 | 0.89 | F10 (0.51) | HTR1AHTR1DHTR2CF10TBXA2R | |
| SCHEMBL2640127 | 0.87 | HTR1A (0.48) | HTR1AHTR1DHTR2CF10ITGB3 | |
| SCHEMBL2640085 | 0.86 | HTR1A (0.47) | HTR1AHTR1DHTR2CF10ITGB3 | |
| SCHEMBL2640150 | 0.86 | HTR1A (0.53) | HTR1AHTR1DHTR2CF10ITGB3 | |
| SCHEMBL2639545 | 0.86 | HTR1A (0.50) | HTR1AHTR1DHTR2CF10TBXA2R | |
| SCHEMBL2639560 | 0.85 | HTR1A (0.45) | HTR1AHTR1DHTR2CTBXA2RITGB3 | |
| SCHEMBL6213045 | 0.85 | F10 (0.47) | HTR1AHTR1DHTR2CF10TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1222182-A2 | SUBSTITUTED (AMINOIMINOMETHYL OR AMINOMETHYL) DIHYDROBENZOFURANS AND BENOZOPYRANS | Aventis Pharmaceuticals Inc. (US) | 2002-07-17 | — | — | EP | disclosed |
| WO-2001014358-A2 | SUBSTITUTED (AMINOIMINOMETHYL OR AMINOMETHYL) DIHYDROBENZOFURANS AND BENOZOPYRANS | AVENTIS PHARMACEUTICALS INC. (DE) | 2001-03-01 | — | — | WO | disclosed |