SCHEMBL263978

SCHEMBL263978

Clc1ccc(C2CNCCN2)cc1

nearest known ligand 0.53

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HTR3A P46098 1/20 0.53
SLC6A2 P23975 2/20 0.41
SLC6A3 Q01959 2/20 0.41
PRCP P42785 1/20 0.39
CHRNA7 P36544 1/20 0.39
SLC6A4 P31645 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1673686 1.00 HTR3A (0.53) HTR3ASLC6A2SLC6A3PRCPCHRNA7
Hydrochloric Acid SCHEMBL1673491 0.98 HTR3A (0.52) HTR3ASLC6A2SLC6A3PRCPCHRNA7
Hydrochloric Acid SCHEMBL2031988 0.98 HTR3A (0.52) HTR3ASLC6A2SLC6A3PRCPCHRNA7
Hydrochloric Acid SCHEMBL1673492 0.98 HTR3A (0.52) HTR3ASLC6A2SLC6A3PRCPCHRNA7
SCHEMBL27292102 0.91 HTR3A (0.46) HTR3ASLC6A2SLC6A3CHRNA7
SCHEMBL1069753 0.83 SLC6A3 (0.48) HTR3ASLC6A2SLC6A3PRCPCHRNA7
SCHEMBL12537047 0.82 HTR3A (0.52) HTR3ASLC6A2SLC6A3PRCPCHRNA7
SCHEMBL4467879 0.82 HTR3A (0.46) HTR3ASLC6A2SLC6A3PRCPCHRNA7
SCHEMBL552751 0.80 MAPT (0.43)
SCHEMBL10563871 0.80 PARP1 (0.35) HTR3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104046246-B The chemical-mechanical planarization of tungsten-containing substrate 气体产品与化学公司 2016-06-15 CN claimed
US-20140273458-A1 Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-18 US claimed
EP-2779217-A2 Chemical mechanical planarization for tungsten-containing substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-17 EP claimed
CN-104046246-A Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PROD & CHEM 2014-09-17 CN claimed
US-4705788-A Novel antibacterial 7-amino-1(substituted cyclopropyl)-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids BAYER AKTIENGESELLSCHAFT (DE) 1987-11-10 US claimed
EP-0211746-A1 Phenyl-piperazine derivatives, process for their preparation and therapeutical use LABORATOIRE L. LAFON Société anonyme dite: (FR) 1987-02-25 EP claimed
WO-2025106722-A1 INHIBITORS OF STK33, RET, CLK, AND/OR RELATED KINASES AND METHODS USING SAME BAYLOR COLLEGE OF MEDICINE (US) 2025-05-22 WO disclosed
CN-110515268-A Photosensitve resin composition, the hardening thing of the Photosensitve resin composition and the display device containing the hardening thing NIPPON STEEL CHEMICAL & MAT CO LTD 2019-11-29 CN disclosed
CN-110256655-A A kind of tannic acid Quito official's epoxy resin and preparation method thereof and preparation can liquid alkali developing negative photoresist 苏州瑞红电子化学品有限公司 2019-09-20 CN disclosed
CN-106573932-B Indazoles 默克专利股份公司 2019-07-30 CN disclosed
EP-3183239-B1 INDAZOLES MERCK PATENT GMBH (DE) 2018-09-26 EP disclosed
US-9862717-B2 Indazoles MERCK PATENT GMBH (DE) 2018-01-09 US disclosed
US-20170267675-A1 INDAZOLES MERCK PATENT GMBH (DE) 2017-09-21 US disclosed
EP-0201829-A1 1-Aryl-4-quinolone-3-carboxylic acids BAYER AG (DE) 1986-11-20 EP disclosed
EP-0198192-A1 7-Amino-1-(subst.cyclopropyl)-1,4 -dihydro-4-oxo-quinoline carboxylic acids, method for their preparation, and antibacterial agents containing them BAYER AG (DE) 1986-10-22 EP disclosed
EP-0187376-A2 6,7-Disubstituted 1-cyclopropyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acids BAYER AG (DE) 1986-07-16 EP disclosed
US-4599334-A 7-(3-aryl-1-piperazinyl)- and 7-(3-cyclohexyl-1-piperazinyl)-3-quinolonecarboxylic acid antibacterials BAYER AKTIENGESELLSCHAFT (DE) 1986-07-08 US disclosed
EP-0169993-A2 7-(3-Aryl-1-piperazinyl) and 7-(3-cyclohexyl-1-piperazinyl) 3-quinoline carboxylic acids BAYER AG (DE) 1986-02-05 EP disclosed
EP-0167763-A1 7-Amino-1-cyclopropyl-6,8-dihalo-1,4-dihydro-4-oxo-3-quinoline-carboxylic acids, process for their preparation and bactericidal agents containing them BAYER AG (DE) 1986-01-15 EP disclosed
EP-0164619-A1 2,4,5-Trihalo or 2,3,4,5-tetrahalo benzene derivatives and process for producing them BAYER AG (DE) 1985-12-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170267675-A1 INDAZOLES MKI67, CCNI, BRCA1 HTR3A 3246/4885SLC6A2 4789/4885SLC6A3 4592/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.