Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | PRCP | P42785 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4467879 | 0.84 | HTR3A (0.46) | SLC6A3SLC6A2SLC6A4HTR3ALMNA | |
| SCHEMBL1673686 | 0.83 | HTR3A (0.53) | SLC6A3SLC6A2SLC6A4HTR3APRCP | |
| SCHEMBL263978 | 0.83 | HTR3A (0.53) | SLC6A3SLC6A2SLC6A4HTR3APRCP | |
| Hydrochloric Acid SCHEMBL2031988 | 0.81 | HTR3A (0.52) | SLC6A3SLC6A2SLC6A4HTR3APRCP | |
| Hydrochloric Acid SCHEMBL1673491 | 0.81 | HTR3A (0.52) | SLC6A3SLC6A2SLC6A4HTR3APRCP | |
| Hydrochloric Acid SCHEMBL1673492 | 0.81 | HTR3A (0.52) | SLC6A3SLC6A2SLC6A4HTR3APRCP | |
| SCHEMBL170771 | 0.80 | HTR3A (0.50) | SLC6A3SLC6A2SLC6A4HTR3ALMNA | |
| SCHEMBL29081932 | 0.80 | HTR3A (0.42) | SLC6A3SLC6A2SLC6A4HTR3APRCP | |
| SCHEMBL12549830 | 0.78 | SLC6A3 (0.45) | SLC6A3SLC6A2SLC6A4HTR3AALDH1A1 | |
| SCHEMBL1673367 | 0.75 | CHRNB2 (0.50) | SLC6A3SLC6A2SLC6A4HTR3ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2394989-A1 | Method for producing a N-substituted aziridine | BASF SE (DE) | 2011-12-14 | — | — | EP | disclosed |
| EP-2275408-A1 | Method for synthesizing a n-substituted aziridine | BASF SE (DE) | 2011-01-19 | — | — | EP | disclosed |
| US-20100191000-A1 | METHOD FOR SYNTHESIZING AN N-UNSUBSTITUTED OR N-SUBSTITUTED AZIRIDINE | BASF SE (DE) | 2010-07-29 | — | — | US | disclosed |
| CN-101679234-A | Method for synthesizing N-unsubstituted or N-substituted aziridine | BASF SE | 2010-03-24 | — | — | CN | disclosed |
| EP-2160379-A1 | METHOD FOR SYNTHESIZING AN N-UNSUBSTITUTED OR N-SUBSTITUTED AZIRIDINE | BASF SE (DE) | 2010-03-10 | — | — | EP | disclosed |
| WO-2008155355-A1 | METHOD FOR SYNTHESIZING AN N-UNSUBSTITUTED OR N-SUBSTITUTED AZIRIDINE | BASF SE (DE) | 2008-12-24 | — | — | WO | disclosed |
| US-6974874-B2 | Reduction of monomer content and stabilization of polyaziridines | BAYER MATERIALSCIENCE LLC (US) | 2005-12-13 | — | — | US | disclosed |
| US-6927297-B2 | Reduction of monomer content and stabilization of polyaziridines | BAYER MATERIALSCIENCE LLC (US) | 2005-08-09 | — | — | US | disclosed |
| US-20040087762-A1 | Reduction of monomer content and stabilization of polyaziridines | COVESTRO LLC | 2004-05-06 | — | — | US | disclosed |
| US-20040087763-A1 | Reduction of monomer content and stabilization of polyaziridines | COVESTRO LLC | 2004-05-06 | — | — | US | disclosed |
| EP-0158874-A2 | Curable iminated resins from aminoplasts and hydroxylcontaining carboxylic acids | PPG INDUSTRIES, INC. (US) | 1985-10-23 | — | — | EP | disclosed |
| US-4293457-A | POLYESTER; AMINOPLAST CURING AGENT; THERMOPLASTIC ACRYLIC POLYMER; CELLULOSE ACETATE BUTYRATE, EPOXY RESIN, OR VINYL ESTER-VINYL HALIDE COPOLYMER | PPG INDUSTRIES, INC. (US) | 1981-10-06 | — | — | US | disclosed |
| US-4232090-A | Sealerless primers | PPG INDUSTRIES, INC. (US) | 1980-11-04 | — | — | US | disclosed |
| US-4225480-A | Addition interpolymers having improved stability and two-package compositions comprising such interpolymers and polyepoxides | PPG INDUSTRIES, INC. (US) | 1980-09-30 | — | — | US | disclosed |
| US-4221885-A | COATINGS; ACRYLIC ACID-ESTER COPOLYMERS, IMINATED AND NEUTRALIZED | PPG INDUSTRIES, INC. (US) | 1980-09-09 | — | — | US | disclosed |
| US-4187258-A | AMINOPLAST CURING AGENT; POLYESTER, POLYETHER, OR POLYURETHANE, THERMOPLASTIC ACRYLIC RESIN | PPG INDUSTRIES, INC. (US) | 1980-02-05 | — | — | US | disclosed |
| US-4126596-A | INTERPOLYMER CONTAINING CARBOXYL GROUPS, ANIONIC SALT GROUPS AND AMINE GROUPS | PPG INDUSTRIES, INC. (US) | 1978-11-21 | — | — | US | disclosed |
| US-4104230-A | POLYEPOXIDES, COPOLYMERS CONTAINING PENDANT SALT GROUPS | PPG INDUSTRIES, INC. (US) | 1978-08-01 | — | — | US | disclosed |
| US-4018849-A | Polyurethane polyol compositions modified with an alkylenimine | PPG INDUSTRIES, INC. (US) | 1977-04-19 | — | — | US | disclosed |
| US-3966667-A | Preparation of non-aqueous thermosetting acrylic polymer dispersions | PPG INDUSTRIES, INC. (US) | 1976-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100191000-A1 | METHOD FOR SYNTHESIZING AN N-UNSUBSTITUTED OR N-SUBSTITUTED AZIRIDINE | CBR1, CBR3, AOC2 | SLC6A3 2138/4885SLC6A2 1480/4885SLC6A4 2198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.