Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | CD38 | P28907 | 3/20 | 0.60 |
| ▸ | HTR2A | P28223 | 1/20 | 0.59 |
| ▸ | HTR2C | P28335 | 1/20 | 0.59 |
| ▸ | HTR2B | P41595 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ADH5 | P11766 | 1/20 | 0.51 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8534210 | 0.87 | HTR2A (0.56) | KMT2ACD38HTR2AHTR2CHTR2B | |
| SCHEMBL25135607 | 0.85 | RAB9A (0.57) | KMT2ACD38HTR2BRAB9AMAPT | |
| SCHEMBL30363943 | 0.84 | NPC1 (0.55) | KMT2ACD38HTR2BRAB9ANPC1 | |
| SCHEMBL25135545 | 0.84 | NPC1 (0.55) | KMT2ACD38HTR2BRAB9ANPC1 | |
| SCHEMBL25135626 | 0.81 | CD38 (0.54) | KMT2ACD38HTR2AHTR2CHTR2B | |
| SCHEMBL30363914 | 0.81 | CD38 (0.54) | KMT2ACD38HTR2AHTR2CHTR2B | |
| SCHEMBL25135727 | 0.80 | CD38 (0.61) | KMT2ACD38RAB9ANPC1HPGD | |
| SCHEMBL8537662 | 0.80 | LMNA (0.64) | KMT2ASMN1; SMN2CYP3A4CYP1A2CYP2C19 | |
| SCHEMBL30363676 | 0.79 | CD38 (0.53) | KMT2ACD38HTR2AHTR2CHTR2B | |
| SCHEMBL25135529 | 0.79 | CD38 (0.53) | KMT2ACD38HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192901-A9 | QUINOLINE DERIVATIVES AS MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS | ESCIENT PHARMACEUTICALS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |
| WO-2023192901-A1 | QUINOLINE DERIVATIVES AS MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS | ESCIENT PHARMACEUTICALS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |