Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 4/20 | 0.44 |
| ▸ | AAK1 | Q2M2I8 | 9/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PPIA | P62937 | 1/20 | 0.33 |
| ▸ | FPR3 | P25089 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29346209 | 0.91 | GHSR (0.40) | GHSRBACE1AAK1NPC1RECQL | |
| SCHEMBL30758528 | 0.91 | GHSR (0.40) | GHSRBACE1AAK1NPC1RECQL | |
| SCHEMBL31232553 | 0.87 | GHSR (0.47) | GHSRBACE1ALDH1A1PPIA | |
| SCHEMBL26129956 | 0.87 | GHSR (0.47) | GHSRBACE1ALDH1A1PPIA | |
| SCHEMBL9255997 | 0.86 | GHSR (0.46) | GHSRBACE1SMN1; SMN2PPIA | |
| SCHEMBL5196233 | 0.84 | GHSR (0.61) | GHSRBACE1PPIA | |
| SCHEMBL31232623 | 0.83 | GHSR (0.47) | GHSRBACE1ALDH1A1PPIA | |
| SCHEMBL26130146 | 0.83 | GHSR (0.47) | GHSRBACE1ALDH1A1PPIA | |
| SCHEMBL26129115 | 0.83 | GHSR (0.46) | GHSRBACE1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31232508 | 0.83 | GHSR (0.46) | GHSRBACE1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023190878-A1 | TETRAHYDRONAPHTHALENE DERIVATIVE | Ａｔｒａｎｓｅｎ Ｐｈａｒｍａ株式会社 | 2023-10-05 | — | — | WO | disclosed |