Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 2/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 3/20 | 0.35 |
| ▸ | PPIA | P62937 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | TACR3 | P29371 | 1/20 | 0.31 |
| ▸ | PYGL | P06737 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.30 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9256587 | 0.95 | GHSR (0.46) | GHSRNR1H2BACE1PPIATACR1 | |
| SCHEMBL31232553 | 0.87 | GHSR (0.47) | GHSRBACE1PPIAGAAPYGL | |
| SCHEMBL26129956 | 0.87 | GHSR (0.47) | GHSRBACE1PPIAGAAPYGL | |
| SCHEMBL26401066 | 0.86 | GHSR (0.46) | GHSRBACE1PPIASMN1; SMN2 | |
| SCHEMBL5196233 | 0.84 | GHSR (0.61) | GHSRBACE1PPIAPYGL | |
| SCHEMBL26130146 | 0.83 | GHSR (0.47) | GHSRBACE1PPIAGAA | |
| SCHEMBL31232623 | 0.83 | GHSR (0.47) | GHSRBACE1PPIAGAA | |
| SCHEMBL26129115 | 0.83 | GHSR (0.46) | GHSRBACE1PPIASMN1; SMN2CXCR5 | |
| SCHEMBL31232508 | 0.83 | GHSR (0.46) | GHSRBACE1PPIASMN1; SMN2CXCR5 | |
| SCHEMBL2405143 | 0.82 | NR1H2 (0.43) | GHSRNR1H2CXCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378838-A | FOR USE IN HUMANS | MERCK & CO., INC. (US) | 1995-01-03 | — | — | US | disclosed |
| WO-1994015924-A1 | CHOLECYSTOKININ ANTAGONISTS | MERCK & CO., INC. (US) | 1994-07-21 | — | — | WO | disclosed |