SCHEMBL26401075

SCHEMBL26401075

Cc1cc(-c2c3c(=O)oc(=O)c3c(-c3cc(C)cc(C(F)(F)F)c3)c3c(=O)oc(=O)c23)cc(C(F)(F)F)c1

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 2/20 0.52
MAPT P10636 2/20 0.39
CTSA P10619 1/20 0.37
IKBKB O14920 1/20 0.36
RAPGEF4 Q8WZA2 2/20 0.33
ADCY8 P40145 1/20 0.33
ADCY1 Q08828 1/20 0.33
MAT2A P31153 1/20 0.33
IDH1 O75874 1/20 0.33
RXRA P19793 1/20 0.33
RXRB P28702 1/20 0.33
PGK1 P00558 1/20 0.33
PGK2 P07205 1/20 0.33
PTGS2 P35354 1/20 0.32
AR P10275 1/20 0.32
ELANE P08246 2/20 0.32
XPO1 O14980 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18179462 0.88 NOTUM (0.41) NOTUMIKBKBRXRARXRBAR
SCHEMBL24254767 0.76 IKBKB (0.41) NOTUMMAPTIKBKBRAPGEF4RXRA
SCHEMBL12583213 0.73 NOTUM (0.50) NOTUMMAPTIKBKBRAPGEF4IDH1
SCHEMBL26375464 0.73 NOTUM (0.50) NOTUMMAPTIKBKBRAPGEF4RXRA
SCHEMBL17570537 0.73 NOTUM (0.44) NOTUMMAPTIKBKBRAPGEF4ADCY8
SCHEMBL13949153 0.72 NOTUM (0.49) NOTUMMAPTIKBKBRAPGEF4RXRA
SCHEMBL18180027 0.71 NOTUM (0.44) NOTUMMAPTIKBKBMAT2A
SCHEMBL13170619 0.71 RXRA (0.47) NOTUMRAPGEF4RXRARXRBAR
SCHEMBL24211024 0.70 NOTUM (0.42) NOTUMIKBKBRAPGEF4
SCHEMBL24211025 0.70 RXRA (0.50) NOTUMMAPTRAPGEF4RXRARXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11782344-B2 Photosensitive polyimide compositions FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2023-10-10 US disclosed