Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26408699 | 0.93 | MALT1 (0.47) | KMT2AMALT1CACNA1HHPGDSMN1; SMN2 | |
| SCHEMBL26409298 | 0.88 | MALT1 (0.41) | KMT2AMALT1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL26408939 | 0.87 | NPY5R (0.43) | KMT2ATP53MAPT | |
| SCHEMBL26408948 | 0.87 | SIGMAR1 (0.47) | CACNA1HMAPT | |
| SCHEMBL26408941 | 0.86 | MALT1 (0.36) | KMT2AMALT1CACNA1HMAPTMEN1 | |
| SCHEMBL26408685 | 0.86 | TP53 (0.44) | MGLLKMT2AMALT1TP53MAPT | |
| SCHEMBL26408937 | 0.85 | HRH2 (0.40) | KMT2AMALT1CACNA1HHPGDSMN1; SMN2 | |
| SCHEMBL26408933 | 0.85 | KDR (0.43) | MALT1 | |
| SCHEMBL26408044 | 0.84 | CACNA1H (0.48) | MGLLKMT2ACACNA1HSMN1; SMN2ALDH1A1 | |
| SCHEMBL26408935 | 0.84 | CACNA1H (0.34) | MALT1CACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192675-A1 | T-TYPE CALCIUM CHANNEL MODULATORS COMPRISING AN AZASPIRONONANE CORE AND METHODS OF USE THEREOF | PRAXIS PRECISION MEDICINES, INC. (US) | 2023-10-05 | — | — | WO | disclosed |