Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 2/20 | 0.34 |
| ▸ | BACE1 | P56817 | 4/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.33 |
| ▸ | EIF4E | P06730 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26408699 | 0.88 | MALT1 (0.47) | MALT1CACNA1HMEN1KMT2A | |
| SCHEMBL26408939 | 0.88 | NPY5R (0.43) | MAPTKMT2AABL1EIF4ERET | |
| SCHEMBL26408948 | 0.88 | SIGMAR1 (0.47) | DRD3TMEM97SIGMAR1CACNA1HMAPT | |
| SCHEMBL26408935 | 0.88 | CACNA1H (0.34) | MALT1DRD3TMEM97SIGMAR1CACNA1H | |
| SCHEMBL26408707 | 0.86 | MGLL (0.43) | MALT1CACNA1HMAPTMEN1KMT2A | |
| SCHEMBL26408933 | 0.86 | KDR (0.43) | MALT1DRD3TMEM97SIGMAR1AKT1 | |
| SCHEMBL26408937 | 0.86 | HRH2 (0.40) | MALT1DRD3TMEM97SIGMAR1CACNA1H | |
| SCHEMBL26408693 | 0.86 | LMNA (0.41) | MAPT | |
| SCHEMBL26408685 | 0.84 | TP53 (0.44) | MALT1MAPTKMT2A | |
| SCHEMBL26408701 | 0.82 | NPSR1 (0.49) | DRD3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192675-A1 | T-TYPE CALCIUM CHANNEL MODULATORS COMPRISING AN AZASPIRONONANE CORE AND METHODS OF USE THEREOF | PRAXIS PRECISION MEDICINES, INC. (US) | 2023-10-05 | — | — | WO | disclosed |