SCHEMBL26409595

SCHEMBL26409595

COC(=O)c1cc2c(cc1C)OC(c1ccccc1)(c1ccccc1)O2

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 9/20 0.58
KDM4E B2RXH2 2/20 0.40
LMNA P02545 2/20 0.39
TSHR P16473 2/20 0.39
ALDH1A1 P00352 3/20 0.39
MAPT P10636 3/20 0.39
PLIN1 O60240 1/20 0.39
GLA P06280 1/20 0.39
POLB P06746 1/20 0.39
PKM P14618 1/20 0.39
HPGD P15428 1/20 0.39
MAPK1 P28482 1/20 0.39
PLIN5 Q00G26 1/20 0.39
MCL1 Q07820 1/20 0.39
ABHD5 Q8WTS1 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CFTR P13569 1/20 0.38
HSD17B10 Q99714 1/20 0.38
ALOX5 P09917 2/20 0.38
ALOX15 P16050 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29987973 1.00 CNR1 (0.58) CNR1KDM4ELMNATSHRALDH1A1
SCHEMBL6226020 0.85 CNR1 (0.64) CNR1ALDH1A1
SCHEMBL29988021 0.84 CNR1 (0.57) CNR1KDM4ELMNATSHRALDH1A1
SCHEMBL26409622 0.84 CNR1 (0.57) CNR1KDM4ELMNATSHRALDH1A1
SCHEMBL4481860 0.84 CNR1 (0.62) CNR1ALDH1A1
SCHEMBL29987992 0.81 CNR1 (0.43) CNR1KDM4ELMNATSHRALDH1A1
SCHEMBL26409579 0.81 CNR1 (0.43) CNR1KDM4ELMNATSHRALDH1A1
Lithium Ion SCHEMBL4481864 0.81 CNR1 (0.60) CNR1KDM4EALDH1A1HPGD
SCHEMBL26409610 0.80 CNR1 (0.43) CNR1KDM4EALDH1A1PKMHPGD
SCHEMBL29988638 0.77 L3MBTL1 (0.46) CNR1KDM4ELMNATSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4313980-B1 LACTIVICIN COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL AGENTS FEDORA PHARMACEUTICALS INC (CA) 2026-04-22 EP disclosed
EP-4685147-A2 LACTIVICIN COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL AGENTS Fedora Pharmaceuticals Inc. (CA) 2026-01-28 EP disclosed
US-12528804-B2 Lactivicin compounds, their preparation and use as antibacterial agents FEDORA PHARMACEUTICALS INC. (CA) 2026-01-20 US disclosed
EP-4313980-A1 LACTIVICIN COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL AGENTS Fedora Pharmaceuticals Inc. (CA) 2024-02-07 EP disclosed
US-20230374005-A1 LACTIVICIN COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL AGENTS FEDORA PHARMACEUTICALS INC. (CA) 2023-11-23 US disclosed
US-20230374005-A1 LACTIVICIN COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL AGENTS FEDORA PHARMACEUTICALS INC. (CA) 2023-11-23 US disclosed
US-20230374005-A1 LACTIVICIN COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL AGENTS FEDORA PHARMACEUTICALS INC. (CA) 2023-11-23 US disclosed
US-11780832-B2 Lactivicin compounds, their preparation and use as antibacterial agents FEDORA PHARMACEUTICALS INC. (CA) 2023-10-10 US disclosed
US-11780832-B2 Lactivicin compounds, their preparation and use as antibacterial agents FEDORA PHARMACEUTICALS INC. (CA) 2023-10-10 US disclosed
US-11780832-B2 Lactivicin compounds, their preparation and use as antibacterial agents FEDORA PHARMACEUTICALS INC. (CA) 2023-10-10 US disclosed
US-20220324858-A1 LACTIVICIN COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL AGENTS FEDORA PHARMACEUTICALS INC. (CA) 2022-10-13 US disclosed
WO-2022208356-A1 LACTIVICIN COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL AGENTS FEDORA PHARMACEUTICALS INC. (CA) 2022-10-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12528804-B2 Lactivicin compounds, their preparation and use as antibacterial agents LCT, LPO, CLSPN CNR1 2778/4885KDM4E 4419/4885LMNA 1567/4885
US-20230374005-A1 LACTIVICIN COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL AGENTS LCT, VIP, LPO CNR1 4802/4885KDM4E 4221/4885LMNA 665/4885
US-11780832-B2 Lactivicin compounds, their preparation and use as antibacterial agents LCT, VIP, LPO CNR1 4797/4885KDM4E 4222/4885LMNA 662/4885
US-20220324858-A1 LACTIVICIN COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL AGENTS LCT, VIP, LPO CNR1 4797/4885KDM4E 4222/4885LMNA 662/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.