SCHEMBL26410083

SCHEMBL26410083

CC1(C)CC(Br)(C(=O)O)C1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.39
APLNR P35414 1/20 0.35
CYP2C19 P33261 2/20 0.32
CYP3A4 P08684 1/20 0.32
LMNA P02545 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
HPGD P15428 1/20 0.31
MAPK1 P28482 2/20 0.31
TP53 P04637 1/20 0.31
NFKB1 P19838 1/20 0.31
THPO P40225 1/20 0.31
STAT6 P42226 1/20 0.31
HIF1A Q16665 1/20 0.31
NPC1 O15118 1/20 0.31
GMNN O75496 1/20 0.31
MTOR P42345 1/20 0.31
RAB9A P51151 1/20 0.31
BLM P54132 1/20 0.31
PMP22 Q01453 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26409341 0.71 FFAR3 (0.58) FFAR3APLNRCYP2C19LMNASMN1; SMN2
SCHEMBL16699606 0.71 FFAR3 (0.43) FFAR3APLNRCYP2C19LMNASMN1; SMN2
SCHEMBL2959604 0.69
SCHEMBL10884072 0.69
SCHEMBL5934352 0.69
SCHEMBL11399902 0.69 FFAR3 (0.41) FFAR3APLNRCYP2C19LMNASMN1; SMN2
SCHEMBL26410086 0.67 GAA (0.31) CYP2C19CYP3A4
SCHEMBL28949183 0.67
Hydrochloric Acid SCHEMBL5379755 0.67
Bicarbonate SCHEMBL9842531 0.67 CYP2C19 (0.41) FFAR3APLNRCYP2C19CYP3A4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4313980-B1 LACTIVICIN COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL AGENTS FEDORA PHARMACEUTICALS INC (CA) 2026-04-22 EP disclosed
EP-4685147-A2 LACTIVICIN COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL AGENTS Fedora Pharmaceuticals Inc. (CA) 2026-01-28 EP disclosed
US-12528804-B2 Lactivicin compounds, their preparation and use as antibacterial agents FEDORA PHARMACEUTICALS INC. (CA) 2026-01-20 US disclosed
EP-4313980-A1 LACTIVICIN COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL AGENTS Fedora Pharmaceuticals Inc. (CA) 2024-02-07 EP disclosed
CN-117500802-A LACTIVICIN compounds, their preparation and their use as antibacterial agents 费多拉制药有限公司 2024-02-02 CN disclosed
US-20230374005-A1 LACTIVICIN COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL AGENTS FEDORA PHARMACEUTICALS INC. (CA) 2023-11-23 US disclosed
US-20230374005-A1 LACTIVICIN COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL AGENTS FEDORA PHARMACEUTICALS INC. (CA) 2023-11-23 US disclosed
US-20230374005-A1 LACTIVICIN COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL AGENTS FEDORA PHARMACEUTICALS INC. (CA) 2023-11-23 US disclosed
US-11780832-B2 Lactivicin compounds, their preparation and use as antibacterial agents FEDORA PHARMACEUTICALS INC. (CA) 2023-10-10 US disclosed
US-11780832-B2 Lactivicin compounds, their preparation and use as antibacterial agents FEDORA PHARMACEUTICALS INC. (CA) 2023-10-10 US disclosed
US-11780832-B2 Lactivicin compounds, their preparation and use as antibacterial agents FEDORA PHARMACEUTICALS INC. (CA) 2023-10-10 US disclosed
US-20220324858-A1 LACTIVICIN COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL AGENTS FEDORA PHARMACEUTICALS INC. (CA) 2022-10-13 US disclosed
WO-2022208356-A1 LACTIVICIN COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL AGENTS FEDORA PHARMACEUTICALS INC. (CA) 2022-10-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12528804-B2 Lactivicin compounds, their preparation and use as antibacterial agents LCT, LPO, CLSPN FFAR3 957/4885APLNR 2863/4885CYP2C19 934/4885
US-20230374005-A1 LACTIVICIN COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL AGENTS LCT, VIP, LPO FFAR3 4701/4885APLNR 3906/4885CYP2C19 854/4885
US-11780832-B2 Lactivicin compounds, their preparation and use as antibacterial agents LCT, VIP, LPO FFAR3 4699/4885APLNR 3851/4885CYP2C19 853/4885
US-20220324858-A1 LACTIVICIN COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL AGENTS LCT, VIP, LPO FFAR3 4699/4885APLNR 3851/4885CYP2C19 853/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.