SCHEMBL2641099

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2641342	0.89	HRH3 (0.48)	HTR2CTBXAS1
	SCHEMBL2641132	0.87	HTR2C (0.47)	HTR2CTBXAS1ALDH1A1KDM4EHTR6
	SCHEMBL2641416	0.86	HTR6 (0.46)	HTR2CCYP1A2CYP3A4CASP1ALDH1A1
	SCHEMBL2641183	0.86	KDM4E (0.42)	HTR2CALDH1A1KDM4EHTR6
	SCHEMBL2640922	0.86	HTR1A (0.47)	HTR2CALDH1A1DRD2KDM4EHTR6
	SCHEMBL2641753	0.85	LTA4H (0.47)	HTR2CCYP1A2CYP3A4CASP1ALDH1A1
	SCHEMBL2640994	0.85	HTR2C (0.43)	HTR2CALDH1A1LMNAKDM4EHTR6
	SCHEMBL2641217	0.83	HRH3 (0.47)	HTR2CTBXAS1ALDH1A1CYP2C9HPGD
	SCHEMBL2640904	0.83	LTA4H (0.46)	HTR2CHTR6
	SCHEMBL2641295	0.83	HTR2C (0.40)	HTR2CCYP1A2CYP3A4ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.