Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 3/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4312678 | 0.87 | HTR2C (0.41) | HTR2CHTR6SLC6A2SLC6A4HTR1A | |
| SCHEMBL6046287 | 0.86 | CCNT1 (0.42) | HTR2CHTR6ADRB1CYP2C19USP2 | |
| SCHEMBL4312809 | 0.84 | CYP2C19 (0.49) | HTR2CHTR6ADRB1CYP2C19USP2 | |
| SCHEMBL4309052 | 0.82 | ADRB1 (0.50) | HTR6ADRB1CYP2C19USP2CYP1A2 | |
| SCHEMBL7474730 | 0.81 | CYP2C19 (0.48) | HTR2CHTR6ADRB1CYP2C19USP2 | |
| SCHEMBL4320202 | 0.80 | HTR2C (0.50) | HTR2CHTR6CYP2C19ALDH1A1CYP1A2 | |
| SCHEMBL2641702 | 0.79 | HTR2C (0.42) | HTR2CHTR6ADRB1CYP2C19USP2 | |
| SCHEMBL4319475 | 0.79 | HTR2C (0.42) | HTR2CHTR6ALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL4322355 | 0.79 | HTR2C (0.50) | HTR2CHTR6SLC6A2HTR1A | |
| SCHEMBL4315672 | 0.78 | ADRB1 (0.52) | HTR2CHTR6ADRB1CYP2C19USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4831903-B2 | — | — | 2011-12-07 | — | — | JP | claimed |
| EP-1178973-A2 | NOVEL COMPOUNDS, THEIR USE AND PREPARATION | Pharmacia AB (SE) | 2002-02-13 | — | — | EP | claimed |
| WO-2000076984-A2 | NOVEL COMPOUNDS, THEIR USE AND PREPARATION | BIOVITRUM AB (SE) | 2000-12-21 | — | — | WO | claimed |