Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.35 |
| ▸ | EED | O75530 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3551334 | 0.72 | SLC6A9 (0.44) | — | |
| SCHEMBL3558414 | 0.72 | SLC6A9 (0.44) | — | |
| SCHEMBL3556320 | 0.68 | SLC6A9 (0.43) | — | |
| SCHEMBL3436283 | 0.66 | SLC6A9 (0.53) | DRD2 | |
| SCHEMBL3436282 | 0.66 | SLC6A9 (0.53) | DRD2 | |
| SCHEMBL5983985 | 0.66 | MAPT (0.41) | HTR1ADRD2MMP2ADAMTS5 | |
| SCHEMBL288996 | 0.62 | MAOB (0.46) | — | |
| SCHEMBL29822798 | 0.62 | MAOB (0.46) | — | |
| SCHEMBL2610674 | 0.61 | GABRA1 (0.46) | EED | |
| SCHEMBL1602646 | 0.60 | EED (0.42) | HTR1ADRD2EED |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4739230-B2 | — | — | 2011-08-03 | — | — | JP | claimed |
| JP-2007514745-A | — | — | 2007-06-07 | — | — | JP | claimed |
| EP-1694663-A1 | NOVEL BENZOFURAN DERIVATIVES, WHICH CAN BE USED IN PROPHYLAXIS OR TREATMENT OF 5-HT6 RECEPTOR-RELATED DISORDER | Biovitrum Aktiebolag (SE) | 2006-08-30 | — | — | EP | claimed |
| WO-2005058858-A1 | NOVEL BENZOFURAN DERIVATIVES, WHICH CAN BE USED IN PROPHYLAXIS OR TREATMENT OF 5-HT6 RECEPTOR-RELATED DISORDER | BIOVITRUM AB (SE) | 2005-06-30 | — | — | WO | claimed |