SCHEMBL288996

SCHEMBL288996

Cc1cccc2ccoc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.46
MAOA P21397 1/20 0.46
SLC6A2 P23975 1/20 0.41
SLC6A4 P31645 1/20 0.41
SLC6A3 Q01959 1/20 0.41
MEN1 O00255 1/20 0.41
NPC1 O15118 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
MAPT P10636 1/20 0.41
MAPK1 P28482 1/20 0.41
CASP3 P42574 1/20 0.41
RAB9A P51151 1/20 0.41
KMT2A Q03164 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
SENP8 Q96LD8 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
SENP6 Q9GZR1 1/20 0.41
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29822798 1.00 MAOB (0.46) MAOBMAOASLC6A2SLC6A4SLC6A3
SCHEMBL12938603 0.72 POLQ (0.39) MAOBMAOAMEN1NPC1CYP1A2
SCHEMBL288995 0.71 MEN1 (0.38) SLC6A2SLC6A4SLC6A3MEN1NPC1
SCHEMBL104411 0.71 MEN1 (0.38) SLC6A2SLC6A4SLC6A3MEN1NPC1
SCHEMBL5424464 0.71 MEN1 (0.38) SLC6A2SLC6A4SLC6A3MEN1NPC1
SCHEMBL2589546 0.71 MEN1 (0.38) SLC6A2SLC6A4SLC6A3MEN1NPC1
SCHEMBL276858 0.71 MEN1 (0.38) MAOBMAOASLC6A2SLC6A4SLC6A3
SCHEMBL3798990 0.71 CYP1A2 (0.41) MEN1NPC1CYP1A2CYP3A4CYP2D6
SCHEMBL954406 0.71 CYP1A2 (0.38) MAOBMAOASLC6A3CYP1A2CYP3A4
SCHEMBL276859 0.71 ADORA2A (0.42) MAOBMAOAMEN1NPC1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 625 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3082884-B1 AIR CARE AND CLEANING PRODUCTS CONTAINING CNGA2 ANTAGONISTS HENKEL AG & CO KGAA (DE) 2018-02-28 EP claimed
EP-3083910-B1 USE OF CNGA2 AGONISTS FOR ENHANCING THE OLFACTORY EFFECT OF AN ODORANT HENKEL AG & CO KGAA (DE) 2017-09-06 EP claimed
EP-3082884-A1 AIR CARE AND CLEANING PRODUCTS CONTAINING CNGA2 ANTAGONISTS Henkel AG & Co. KGaA (DE) 2016-10-26 EP claimed
EP-3083910-A1 USE OF CNGA2 AGONISTS FOR ENHANCING THE OLFACTORY EFFECT OF AN ODORANT Henkel AG & Co. KGaA (DE) 2016-10-26 EP claimed
US-20160289594-A1 USE OF CNGA2 AGONISTS FOR ENHANCING THE OLFACTORY EFFECT OF AN ODORANT HENKEL AG & CO. KGAA (DE) 2016-10-06 US claimed
WO-2015091056-A1 USE OF CNGA2 AGONISTS FOR ENHANCING THE OLFACTORY EFFECT OF AN ODORANT HENKEL AG & CO. KGAA (DE) 2015-06-25 WO claimed
WO-2015091055-A1 AIR CARE AND CLEANING PRODUCTS CONTAINING CNGA2 ANTAGONISTS HENKEL AG & CO. KGAA (DE) 2015-06-25 WO claimed
US-4113891-A BENZOFURANS FIRMENICH & CIE (CH) 1978-09-12 US claimed
EP-3164465-B1 IMPROVED PROCESSES FOR RECOVERING VALUABLE COMPONENTS FROM A CATALYTIC FAST PYROLYSIS PROCESS ANELLOTECH INC (US) 2025-10-29 EP disclosed
CN-118974037-A Benzobicyclo compound and preparation method and application thereof 广州市联瑞制药有限公司 2024-11-15 CN disclosed
US-12048238-B2 Organometallic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2024-07-23 US disclosed
US-20240244858-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2024-07-18 US disclosed
US-20240244952-A1 ORGANIC LIGHT-EMITTING DEVICE AND ORGANOMETALLIC COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2024-07-18 US disclosed
US-20240239824-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2024-07-18 US disclosed
US-3952026-A FLAVOR ADDITIVE FOR FOODS AND BEVERAGES FIRMENICH & CIE (CH) 1976-04-20 US disclosed
US-3952024-A FLAVOR ADDITIVE FOR FOODS AND BEVERAGES FIRMENICH & CIE (CH) 1976-04-20 US disclosed
US-3943260-A TETRAHYDRO-THIO-PHEN-3-ONES FIRMENICH & CIE (CH) 1976-03-09 US disclosed
US-3931166-A FLAVORANTS FIRMENICH & CIE (CH) 1976-01-06 US disclosed
US-3931246-A FURYLALKYL-THIOETHERS FIRMENICH & CIE (CH) 1976-01-06 US disclosed
US-3931245-A FURYLALKYLTHIOL CARBOXYLATES FIRMENICH & CIE (CH) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160289594-A1 USE OF CNGA2 AGONISTS FOR ENHANCING THE OLFACTORY EFFECT OF AN ODORANT CNR2, OR51E2, CHRNA2 MAOB 1682/4885MAOA 1466/4885SLC6A2 877/4885
US-20240244952-A1 ORGANIC LIGHT-EMITTING DEVICE AND ORGANOMETALLIC COMPOUND LEF1, OCIAD1, OXA1L MAOB 1259/4885MAOA 799/4885SLC6A2 4342/4885
US-12048238-B2 Organometallic compound and organic light-emitting device including the same TRPC1, PPOX, LAGE3 MAOB 4401/4885MAOA 3176/4885SLC6A2 4610/4885
US-20240244858-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE CRY1, CRY2, C1S MAOB 1449/4885MAOA 1868/4885SLC6A2 4100/4885
US-20240239824-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE C1S, CHRM1, L1CAM MAOB 1628/4885MAOA 2076/4885SLC6A2 4403/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.