Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.76 |
| ▸ | NPC1 | O15118 | 6/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | BACE1 | P56817 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.55 |
| ▸ | HTR3B | O95264 | 1/20 | 0.55 |
| ▸ | HTR3A | P46098 | 1/20 | 0.55 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.55 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20590676 | 0.86 | RAB9A (0.59) | RAB9ANPC1ALDH1A1KMT2AKDM4E | |
| SCHEMBL21489827 | 0.86 | RAB9A (0.59) | RAB9ANPC1ALDH1A1HPGDHTT | |
| SCHEMBL19710504 | 0.86 | RAB9A (0.59) | RAB9ANPC1ALDH1A1HPGDHTT | |
| SCHEMBL8314705 | 0.82 | RAB9A (0.55) | RAB9ANPC1ALDH1A1KMT2ABACE1 | |
| SCHEMBL21489781 | 0.82 | SMYD3 (0.70) | RAB9ANPC1HPGDHTTHDAC1 | |
| SCHEMBL19710071 | 0.82 | SMYD3 (0.70) | RAB9ANPC1HPGDHTTHDAC1 | |
| SCHEMBL25224750 | 0.82 | ALDH1A1 (0.59) | RAB9ANPC1ALDH1A1KMT2AKDM4E | |
| SCHEMBL5265256 | 0.81 | RAB9A (0.57) | RAB9ANPC1ALDH1A1KMT2ABACE1 | |
| SCHEMBL29176340 | 0.81 | ALDH1A1 (0.54) | RAB9ANPC1ALDH1A1KMT2ABACE1 | |
| SCHEMBL9235867 | 0.81 | RAB9A (0.56) | RAB9ANPC1ALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192901-A9 | QUINOLINE DERIVATIVES AS MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS | ESCIENT PHARMACEUTICALS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |
| WO-2023192901-A1 | QUINOLINE DERIVATIVES AS MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS | ESCIENT PHARMACEUTICALS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |