Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5270583 | 0.84 | RAB9A (0.51) | RAB9ANPC1KMT2AMEN1HTT | |
| SCHEMBL26414747 | 0.81 | RAB9A (0.76) | RAB9ANPC1KMT2AMEN1ACKR3 | |
| SCHEMBL5266990 | 0.81 | CFTR (0.60) | RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL5269272 | 0.81 | KDM4E (0.55) | RAB9ANPC1KMT2AMEN1HTT | |
| SCHEMBL5265813 | 0.80 | NPC1 (0.51) | RAB9ANPC1KMT2AMEN1HTT | |
| SCHEMBL5265463 | 0.78 | RAB9A (0.57) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4282985 | 0.78 | GRM5 (0.56) | RAB9ANPC1SMN1; SMN2HDAC1HDAC6 | |
| SCHEMBL954274 | 0.77 | NPC1 (0.54) | NPC1KMT2AMEN1 | |
| SCHEMBL4292371 | 0.77 | GRM5 (0.55) | RAB9ANPC1ACKR3SMN1; SMN2ALDH1A1 | |
| SCHEMBL4289696 | 0.77 | ALDH1A1 (0.49) | RAB9ANPC1KMT2AMEN1ACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |